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|本期目录/Table of Contents|

联合踝臂指数和钙化积分判定老年冠脉3支病变的价值

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第3期
页码:
403-406
栏目:
临床研究
出版日期:
2009-05-15

文章信息/Info

Title:
Combination of ankle-brachial index and coronary artery calcium score as a predictor for 3-vessel coronary artery disease
作者:
蓝运竞杨成明王旭开曾春雨方玉强
第三军医大学大坪医院野战外科研究所心血管内科,重庆 400042
Author(s):
LAN Yun-jing YANG Cheng-ming WANG Xu-kai ZENG Chun-yu FANG Yu-qiang
Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing 400042, China
关键词:
冠状动脉疾病3支病变踝臂指数钙化积分冠状动脉造影
Keywords:
coronary disease 3-vessel disease ankle-brachial index coronary artery calcium score coronary angiography
分类号:
R541. 4
DOI:
-
文献标识码:
A
摘要:
目的 探讨联合应用踝臂指数(ankle-brachial index,ABI)和钙化积分(coronary artery calcium score,CACS)提高判定冠状动脉3支病变的价值。方法 选择连续96例行冠脉造影的老年患者,分别予ABI检测和64排CT检测CACS。结果 ABI<0.9、CACS>400判定冠脉3支病变敏感度分别为58%、64%,特异度分别为87%、86%,联合使用敏感度显著提高(85%),特异度未明显降低(83%)。结论 ABI<0.9、CACS>400一定程度上能够判定老年人冠脉3支病变,联合使用判定价值更大。
Abstract:
AIM To discuss the predictive value of the combination of ankle-brachial index(ABI) and coronary artery calcium score(CACS)for 3-vessel coronary artery disease (CAD). METHODS This study enrolled 96 patients, who underwent ABI measurement and 64-channel multidetector CT , for their CACS before coronary angiography. RESULTS The respective sensitivities of ABI and CACS for 3-vesssel CAD were 58% and 64%, and the specificities were 87.3% and 85%. After combining the two methods, the sensitivity was notably improved to 85%, but the specificity was decreased to 82%. CONCLUSION ABI<0.9 and CACS>400 can be used to predict 3-vessel CAD, but the predictive value is notably improved after the combination of ABI<0.9 and CACS>400.

参考文献/References

[1] Lamina C, Meisinger C, Heid IM, et al. Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up[J]. Eur Heart J, 2006, 27(21):2580-2587.

[2] Budoff MJ, Shaw LJ, Liu ST, et al. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients[J]. J Am Coll Cardiol, 2007, 49(18):1860-1870.

[3] Sukhija R, Aronow WS, Yalamanchili K, et al. Association of ank1e-brachial index with severity of angiographic coronary artery disease in patients with peripheral arterial disease and coronary artery disease[J]. Cardiology, 2005, 103(3):158.

[4] Otah KE, Madan A, Otah E, et al. Usefullness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-Americans[J]. Am J Cardiol, 2004, 93(4):48l-483.

[5] 俞高龙,李海兵,张明华,等. 多层螺旋CT量化冠状动脉钙化的评价[J]. 心脏杂志, 2004,16(4): 335-338.

[6] Greenland P, Abrams J, Aurigemma G P, et al. Prevention conference V: beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III[J]. Circulation, 2000, 101(1):16-22.

[7] Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography[J]. J Am Coll Cardiol, 1990, 15(4):827-832.

[8] Greenland P, Bonow RO, Brundage BH, et al. ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography) developed in collaboration with the Society of Atherosclerosis Imaging and Prevention and the Society of Cardiovascular Computed Tomography[J]. J Am Coll Cardiol, 2007, 49(3):378-402.

[9] 张剑,韩雅玲,荆全民,等. 多支慢性完全闭塞冠脉病变患者临床及冠脉造影特征[J]. 心脏杂志, 2007, 19(5):563-564.

[10]Sechtem U, Vohringer M. The clinical role of ‘non-invasive’ coronary angiography by multidetector spiral computed tomography: yet to be defined[J]. Eur Heart J, 2005, 26(19):942-1944.

备注/Memo

备注/Memo:
收稿日期:2007-8-20.通讯作者:杨成明,教授,主任医师,主要从事动脉粥样硬化 基础与临床研究Email:yangchmi@163.com 作者简介:蓝运竞,硕士生Email:lyj1977@sina.com
更新日期/Last Update: 2009-05-18