我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

环氧氯丙烷处理牛颈静脉带瓣管道生物学特性的研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第4期
页码:
500-502
栏目:
基础研究
出版日期:
2009-06-25

文章信息/Info

Title:
Biological characteristics of bovine jugular vein conduit fixed with epoxy chloropropan
作者:
朱海龙1; 刘洋1; 刘珊珊2; 孙国成1; 郑奇军1; 易定华1; 刘维永1
第四军医大学:1．西京医院心脏外科，陕西 西安 710032，2．唐都医院超声诊断科，陕西 西安 710038
Author(s):
ZHU Hai-long1;  LIU Yang1;  LIU Shan-shan2;  SUN Guo-cheng1;  ZHENG Qi-jun1;  YI Ding-hua1;  LIU Wei-yong1
1.Department of Cardiac Surgery, Xijing Hospital, Xian 710032, Shaanxi, China, 2.Department of Ultrasound Diagnosis, Tangdu Hospital, Forth Military Medical University, Xian 710038, Shaanxi, China
关键词:
环氧氯丙烷; 戊二醛; 牛颈静脉带瓣管道
Keywords:
epoxy chloropropan;  glutaraldehyde;  bovine jugular vein conduit
分类号:
R654.2
DOI:
-
文献标识码:
A
摘要:
目的 评价环氧氯丙烷处理牛颈静脉带瓣管道（BJVC)的生物学特性。方法 分别比较戊二醛处理、环氧氯丙烷处理、戊二醛+环氧氯丙烷联合处理和新鲜BJVC的管壁、瓣膜的厚度、大体形态、组织学特点、含水量、热皱缩温度及断裂强度，并进行可溶性蛋白含量的测定。结果 戊二醛+环氧氯丙烷联合处理组BJVC的管壁、瓣膜厚度、组织含水量与未处理组相比较无明显变化；但管壁、瓣膜断裂强度和热皱缩温度均较新鲜对照组明显提高(P<0.05)，可溶性蛋白的含量明显减少(P<0.05)。结论 戊二醛+环氧氯丙烷联合处理的带瓣管道材料具有较好的生物学特性。
Abstract:
AIM: To evaluate the biological characteristics of bovine jugular vein conduit fixed with epoxy chloropropan. METHODS: Thickness, appearance, histology, water content, shrinkage temperature, breaking strength and soluble protein level of the wall and valve of bovine jugular vein conduit fixed, respectively, with glutaraldehyde, epoxy chloropropan, glutaraldehyde plus epoxy chloropropan were analyzed and compared with fresh ones. RESULTS: Thickness, appearance, histology, water content of wall and valve of bovine jugular vein conduit fixed with glutaraldehyde and epoxy chloropropan were similar to those of fresh ones. Although the shrinkage temperature and breaking strength were improved, soluble protein level markedly decreased. CONCLUSION: Bovine jugular vein conduit fixed with epoxy chloropropan shows good biological characteristics.

参考文献/References

［1］ Clarke DR, Bishop DA. Ten year experience with pulmonary allografts in children［J］. J Heart Valve Dis, 1995, 4(4):384-391.

［2］ Tam RK, Tolan MJ, Zamvar VY, et al. Use of larger sized aortic homograft conduits in right ventricular outflow tract reconstruction［J］. J Heart Valve Dis, 1995, 4(6):660-664.

［3］ Pearl JM, Cooper DS, Bove KE, et al. Early failure of the shelhigh pulmonary valve conduit in infants［J］. Ann Thora Surg, 2002, 74(2):542-549.

［4］ Boethig D, Thies WR, Hecker H, et al. Mid term course after pediatric right ventricular outflow tractreconstruction: a comparison of homografts, porcinexenografts and Contegras［J］. Eur J Cardiothorac Surg, 2005, 27(1):58-66.

［5］ Delmo-Walter EM, Alexi-Meskishvili V, Abdul-Khaliq H, et al. Aneurysmal dilatation of the contegra bovine jugular vein conduit after reconstruction of the right ventricular outflow tract ［J］ . Ann Thorac Surg, 2007, 83(2):682-684.

［6］ Gober V, Berdat P, Pavlovic M, et al. Adverse mid-term outcome following RVOT reconstruction using the Contegra valved bovine jugular vein［J］. Ann Thorac Surg, 2005, 79(2):625-631.

［7］ Chang Y, Hsu CK, Wei HJ, et al. Cell-free xenogenic vascular grafts fixed with glutaraldehyde or genipin: In vitro and in vivo studies［J］. J Biotechnol, 2005, 120(2):207-219.

［8］ 易定华，刘维永，杨景学，等. 生物心脏瓣膜钙化机理及抗钙化研究［J］. 中华外科杂志， 1996， 34(10)：631-633.

备注/Memo

备注/Memo:
收稿日期：2008-3-24.基金项目：国家高技术研究发展计划（863计划）课题项目资助(2006AA02A138)；陕西省科技攻关课题项目资助［2007K11-03（1）］ 作者简介：朱海龙，副教授，副主任医师，博士Email：zhlgzb@fmmu.edu.cn
更新日期/Last Update: 2009-06-15