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|本期目录/Table of Contents|

冠心病患者冠状动脉病变与心脏功能的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第5期
页码:
672-674
栏目:
临床研究
出版日期:
2009-07-14

文章信息/Info

Title:
Relationship between severity of coronary artery lesions and cardiac function
作者:
王子宽; 柳荫; 何勇; 张录兴; 刘军; 郑强荪
第四军医大学第二附属医院心内科,陕西 西安 710038
Author(s):
WANG Zi-kuan;  LIU Yin;  HE Yong;  ZHANG Lu-xing;  LIU Jun;  ZHENG Qiang-sun
Department of Cardiology, Second Affiliated Hospital, Fourth Military Medical University, Xian 710032, Shaanxi, China
关键词:
冠状动脉疾病; 心脏超声; 狭窄程度; 病变范围
Keywords:
coronary disease;  heart ultrasonography;  scope of coronary artery stenosis;  degree of coronary artery stenosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 探讨冠状动脉病变范围及狭窄程度与心脏功能的关系。方法: 选择性冠状动脉造影387例，冠状动脉造影证实冠心病患者252例，按病变范围、狭窄程度分组，术前行心脏超声检查，对比分析冠状动脉病变范围及狭窄程度与功能的关系。结果: 冠状动脉轻、中度狭窄、1支病变时，左室收缩功能改变不明显，舒张功能出现减退(P<0.05或P<0.01)。冠状动脉重度狭窄、完全闭塞时，舒张功能明显减退(P<0.01)，收缩功能与受累血管数量、病变程度有明显相关性。结论: 冠状动脉病变对心脏的功能有一定影响，冠心病患者心脏舒张功能减退先于收缩功能。
Abstract:
AIM: To investigate the relationship between the scope and degree of coronary artery stenosis and the function of the heart. METHODS: We studied 387 patients who underwent selective coronary arteriography (CAG). The 252 patients who had been diagnosed as having coronary heart disease (CAD) by CAG were divided into different groups according to the extent of the lesion and the stenosis of the artery. All patients were examined by heart ultrasonography before CAG. On the basis of the CAG and heart ultrasonography results, we analyzed the correlation between the scope and degree of coronary artery stenosis and the function of the heart. RESULTS: In the patients with low- to medium-grade stenosis or with one stenosed coronary artery, only the diastolic function of the left ventricle decreased (P<0.05 or P<0.01). In patients with high-grade stenosis and total occlusion, both the diastolic and systolic function of the left ventricle decreased and the decreased degree of contractile function had a significant correlation with the number and severity of involved coronary arteries (P<0.01). CONCLUSION: The severity of coronary stenosis influences the function of the heart. In patients with CAD, the diastolic function of the heart decreases before the systolic function.

参考文献/References

［1］ 任文武,华琦,魏嘉萍. 冠心病左室结构与功能相关关系的临床分析［J］. 中国医学影像技术, 2002, 18（9）:888-891.

［2］ Oh JK, Appleton CP, Hatle LK, et al. The noninsasive assessment of left ventricular diastolic function with two-dimensional and Doppler echocardiography［J］. J Am Soc Echocardiogr, 1997, 10(3):246-270.

［3］ Smiseth OA. Assessment of ventricular diasolic function［J］. Can J Cardiol, 2001, 17(11):1167-1176.

备注/Memo

备注/Memo:
收稿日期：2008-4-29.通讯作者：郑强荪，教授，主任医师，主要从事心律失常及冠心病诊治研究Email:tdx2nk01@fmmu.edu.cn 柳荫，副教授，副主任医师，主要从事心律失常及冠心病诊治研究Email：tdx2nk01@fmmu.edu.cn 作者简介：王子宽，主治医师，讲师，博士后Email：wangzikuan@sohu.com
更新日期/Last Update: 2009-07-22