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|本期目录/Table of Contents|

单相动作电位技术检测心房复极的电生理特点

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第1期
页码:
84-85,88
栏目:
临床研究
出版日期:
2010-01-04

文章信息/Info

Title:
Preliminary study of atrial electrophysiology using monophasic action potentials technique in patients without structural heart disease
作者:
尹德录; 宋和鉴; 顾建明; 徐惠民; 周艺; 王莹
连云港市第一人民医院心内科，江苏 连云港 222002
Author(s):
YIN De-lu;  SONG He-jian;  GU Jian-ming;  XU Hui-min;  ZHOU Yi;  WANG Ying
Department of Cardiology, First Hospital of Lianyungang City, Lianyungang 222002, Jiangsu, China
关键词:
电生理学; 单相动作电位; 复极离散度; 动作电位时程
Keywords:
electrophysiology;  monophasic action potentials;  repolarization dispersion;  action potential duration
分类号:
R331.38
DOI:
-
文献标识码:
A
摘要:
目的: 探讨应用普通标测电极记录单相动作电位（MAP）的可行性，并对心房电生理特性做初步研究。方法: 阵发性室上性心动过速行射频消融的患者12例，应用两根普通四极标测导管，于高位右房（HRA）和右房低位侧壁（LLW）两点顺序标测记录MAP。结果: 共记录到21个满意的MAP信号，HRA处激动时间（AT）小于LLW处，动作电位时程（APD）和复极时间（RT）则相反（P<0.05或P<0.01），但S1S1刺激时的APD较窦律时缩短（P<0.05），RT离散度明显小于APD离散度（均P<0.01）。结论: 无器质性心脏病者右房区域内存在复极离散。
Abstract:
AIM: To investigate the electrophysiology of the atrium and the feasibility of monophasic action potentials (MAP) recording using a common mapping electrode catheter. METHODS: MAPs were recorded at high and low lateral walls of the right atrium using common four-pole mapping electrodes in 12 patients with paroxysmal supraventricular tachycardia. RESULTS: Twenty one satisfactory MAPs signals were recorded. The action time at high right atrium was shorter than at low lateral right atrium and was reversed in action potential duration (APD) and recovery time (RT) (P<0.05 or P<0.01). APD was shorter in S1S1 stimulation than in sinus rhythm (P<0.05). Dispersion of RT was lower than dispersion of APD (P<0.01). CONCLUSION: Repolarization dispersion and electrophysiology stability exist simultaneously in normal right atrium.

参考文献/References

［1］ Andrikopoulos GK, Dilaveris PE, Richter DJ, et al. Increased variance of P wave duration on the electrocardiogram distinguishes patients with idiopathic paroxysmal atrial fibrillation［J］. Pacing Clin Electrophysiol, 2000, 23(7):1127-1132.

［2］ 尹德录,刘志华,宋建平,等. 正常心室肌复极离散度初步研究［J］. 中华心血管病杂志, 2001, 29(4):227-230.

［3］ 李翠兰,胡大一. 单相动作电位技术及其临床应用［J］.中国心脏起搏与心电生理杂志, 2002, 16(5):326-331.

［4］ Kamalvand K, Tan K, Lloyd G, et al. Alterations in atrial electrophysiology associated with chronic atrial fibrillation in man［J］. Eur Heart J, 1999, 20(12):888-895.

［5］ Okumura Y, Watanabe I, Nakai T, et al. Recurrence of atrial fibrillation after internal cardioversion of persistent atrial fibrillation: prognostic importance of electrophysiologic parameters［J］. Circ J, 2005, 69(12):1514-1520.

［6］ Yuan S, Kongstad O, Hertervig E, et al. Recording monophasic action potentials using a platinum-electrode ablation catheter［J］. Europace, 2000, 2(4):312-319.

［7］ 梁延春,韩雅玲,王祖禄,等. 猪左心室内膜整体复极顺序的单相动作电位标测［J］. 心脏杂志, 2005, 17(5):409-412.

备注/Memo

备注/Memo:
收稿日期：2008-5-13.基金项目：江苏省连云港市卫生局重点人才项目资助（PC03-002） 通讯作者：尹德录，副主任医师，博士，主要从事基础电生理和介入心脏病学研究Email:druseyin@163.com
更新日期/Last Update: 2010-01-05