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|本期目录/Table of Contents|

诱导内皮祖细胞在心肌缺血中的趋化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2011年第3期
页码:
406-407,416
栏目:
综述
出版日期:
2011-05-12

文章信息/Info

Title:
-
作者:
姜萌 综述何奔 审校
上海交通大学医学院附属仁济医院心内科,上海 200001
Author(s):
-
关键词:
内皮祖细胞心肌缺血趋化
Keywords:
-
分类号:
Q813.11
DOI:
-
文献标识码:
A
摘要:
内皮祖细胞(EPCs)移植为促进缺血性疾病局部血管新生、改善低氧提供了新的手段,成为严重缺血性疾病治疗的辅助手段之一;但移植后EPCs靶向性较差导致EPCs利用率的低下,限制了EPCs的广泛应用。因此,发现EPCs在体内趋化的途径,增加EPCs在体内的归巢已经成为目前研究的热点。本文就目前对EPCs趋化的机制,已经发现的趋化通路进行了探讨,提出有待解决的问题,以及可能的进一步研究方向,为可能开展的进一步研究提供了思路。
Abstract:
-

参考文献/References

[1]许爱斌,宋延彬,郭文怡,等.内皮祖细胞移植对兔心肌梗死后心功能的影响[J].心脏杂志,2010,22(1):56-58.
[2]Stellos K,Langer H,Daub K,et al.Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cells[J]. Circulation,2008,117(2):206-215.
[3]Fox A,Smythe J,Fisher N,et al.Mobilization of endothelial progenitor cells into the circulation in burned patients[J].Br J Surg,2008,95(2):244-251.
[4]Schuh A,Liehn EA,Sasse A,et al.Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model[J].Basic Res Cardiol,2008,103(1):69-77.
[5]姜萌,王彬尧,王长谦,等.静脉注射携带缺氧诱导因子的内皮祖细胞对裸鼠缺血下肢血管新生的作用[J].中国动脉硬化杂志,2007,15(8):580-584.
[6]Zemani F,Silvestre JS,Fauvel-Lafeve F,et al.Ex vivo priming of endothelial progenitor cells with SDF-1 before transplantation could increase their proangiogenic potential[J].Arterioscler Thromb Vasc Biol,2008,28(4):644-650.
[7]Zheng H,Fu G,Dai T,et al.Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway[J].J Cardiovasc Pharmacol,2007,50(3):274-280.
[8]尹扬光,黄岚,赵晓辉,等.内皮祖细胞分泌SDF-1及其抗内皮祖细胞凋亡作用[J].心脏杂志,2007,19(4):391-394.
[9]Kocher AA,Schuster MD,Bonaros N,et al.Myocardial homing and neovascularization by human bone marrow angioblasts is regulated by IL-8/Gro CXC chemokines[J].J Mol Cell Cardiol,2006,40(4):455-464.
[10]Hou Y,Plett PA,Ingram DA,et al.Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3[J].Exp Hematol,2006,34(8):1125-1132.
[11]Xu Q,Wang S,Jiang X,et al.Hypoxia-induced astrocytes promote the migration of neural progenitor cells via vascular endothelial factor, stem cell factor, stromal-derived factor-1alpha and monocyte chemoattractant protein-1 upregulation in vitro[J].Clin Exp Pharmacol Physiol,2007,34(7):624-631.
[12]Heiss C,Wong ML,Block VI,et al.Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells[J].J Cell Physiol,2008,215(2):366-373.
[13]Oh IY,Yoon CH,Hur J,et al.Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle[J].Blood,2007,110(12):3891-3899.
[14]Deregibus MC,Cantaluppi V,Calogero R,et al. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA[J]. Blood,2007,110(7):2440-2448.
[15]Chavakis E.IL-8:a new player in the homing of endothelial progenitor cells to ischemic myocardium[J].J Mol Cell Cardiol, 2006,40(4):442-445.
[16]Yu Y,Gao Y,Wang H,et al.The matrix protein CCN1 (CYR61) promotes proliferation, migration and tube formation of endothelial progenitor cells[J].Exp Cell Res,2008,314(17):3198-3208.

备注/Memo

备注/Memo:
收稿日期:2010-03-23.基金项目:国家自然基金项目(30800453);上海市青年科技启明星计划资助(10QA1404500) 通讯作者:何奔,教授,主要从事内皮祖细胞促血管新生的研究Email:heben1025@126.com 作者简介:姜萌,主治医师,博士Email:jiangmeng0919@163.com
更新日期/Last Update: 2011-03-17