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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

2011年第4期

页码:

515

栏目:

临床研究

出版日期:

2011-08-25

文章信息/Info

Title:

Relationship between carotid artery atherosclerosis and coronary heart disease in elderly patients with chronic bronchitis

作者:

苏绍萍¹; 刘丽凤²; 王一茹²; 白静² ; 陈杰²; 王禹²

解放军总医院：1.干部诊疗科，2.老年心血管病研究所，北京 100853

Author(s):

SU Shao-ping¹;  LIU Li-feng²;  WANG Yi-ru²;  BAI Jing²;  CHEN Jie²;  WANG Yu²

1.Department of Clinical Medicine, 2.Institute of Geriatric Cardiology, PLA General Hospital, Beijing 100853, China

关键词:

颈动脉; 冠状动脉; 动脉粥样硬化; 支气管炎; 慢性

Keywords:

carotid artery;  coronary artery disease;  atherosclerosis;  coronary angiography

分类号:

R541.4;R445.1

DOI:

61-1268/R.20110503.1639.024

文献标识码:

A

摘要:

目的:应用多普勒超声分析伴有慢性支气管炎的心绞痛患者颈动脉病变，并分析与冠心病病变的相关性。方法: 选择因心绞痛行冠状动脉造影的患者328例，根据造影结果分为对照组80例、单支病变组102例、2支病变组62例和多支病变组84例。测量颈总动脉内膜中层厚度（IMT）及颈动脉分叉处IMT，记录颈动脉斑块的位置、数量。结果: 颈总动脉IMT、分叉部IMT、斑块积分组间差异有统计学意义（P<0.05，P<0.01）。颈总动脉 IMT多支病变组与对照组（P<0.01）、2支病变组与对照组（P<0.05）、单支病变组与多支病变组（P<0.01）差异有统计学意义，其余组间两两比较无统计学差异。分叉部IMT，单支病变组与对照组差异无统计学意义，其余各组两两之间比较均有统计学差异(P<0.01，P<0.05)。斑块积分，多支病变组与2支病变组间差异无统计学意义，其余组间两两比较均有统计学差异(P<0.01，P<0.05)。颈动脉IMT、分叉部IMT、斑块积分相关系数均有统计学意义（P<0.05）。结论: 伴有慢性支气管炎的老年颈动脉粥样硬化与其冠状动脉病变有相关性。

Abstract:

AIM:To investigate whether the extent of carotid atherosclerosis is associated with coronary heart disease (CHD) in elderly patients with chronic bronchitis. METHODS: Carotid ultrasound was performed in 328 patients. According to the results of coronary angiography, patients were divided into four groups: one-vessel group (n=102), two-vessel group (n=62), multi-vessel group (n=84) and normal control group (n=80). The intima-media thickness (IMT) and the degree of carotid atherosclerosis were compared among the four groups. RESULTS: A statistically significant difference in carotid artery IMT and plaque score was observed between control group and coronary artery disease (CAD) groups (P<0.05), especially between two-vessel and multivessel groups. CONCLUSION: Our findings indicate that carotid atherosclerosis is a good predictive marker for coronary heart disease. Ultrasound examination of the carotid artery is of some value in screening high-risk patients with coronary artery disease.

参考文献/References

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备注/Memo

备注/Memo:

收稿日期：2010-09-25.通讯作者：王禹，主任医师，主要从事冠心病基础与介入临床研究Email:wangyuheart@yahoo.com.cn 作者简介：苏绍萍，副主任医师，硕士Email:sushaoping301@sina.com

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更新日期/Last Update: 2011-06-02