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中老年继发孔型房间隔缺损治疗前后左房形态及功能的变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2012年第2期
页码:
227-229
栏目:
临床研究
出版日期:
2012-04-25

文章信息/Info

Title:
Effects of percutaneous closure of secundum atrial septal defect on size and function of left atrium in patients >40 years of age
作者:
李 伟; 张玉顺; 杜亚娟; 成革胜
(西安交通大学第一附属医院心内二科，陕西 西安 710061)
Author(s):
LI We;  ZHANG Yu-shun;  DU Ya-juan;  CHENG Ge-sheng
(Second Department of Cardiology, First Affiliated Hospital, Medical College, Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China)
关键词:
房间隔缺损; 左房功能; 介入治疗
Keywords:
atrial septal defects;  function of left atrium;  interventional therapy
分类号:
R541.1
DOI:
-
文献标识码:
A
摘要:
目的:分析成人继发孔型房间隔缺损（ASD）封堵术后左房形态及功能变化与年龄的关系。方法：49例成人ASD患者依据年龄分成二组:，<40岁组23（男13，女10）例，年龄20~38（31±12）岁。≥40岁组26（男9，女17）例，年龄40~72（49±14）岁。均于术前、术后2 d、1月、3月、6月行经胸超声心动图（TTE）检查，测量左房左右径及左房相关容积。结果：<40岁组ASD患者封堵术后3月，左房左右径较术前减小（P<0.05），≥40岁组ASD患者封堵术后6月左房左右径较术前减小（P<0.05）；<40岁组ASD患者封堵术后2 d左房储蓄容积较术前减小（P<0.05），≥40岁组ASD患者封堵术后6月较术前明显减小(P<0.05)；<40岁组ASD患者封堵术后3月左房被动排空容积较术前明显缩小（P<0.05），≥40岁组ASD患者封堵术后6个月时才明显缩小（P<0.01）；<40岁组ASD患者封堵术后1月，LAEF较术前明显增加（P<0.01）,≥40岁组ASD患者封堵术后3个月，LAEF较术前明显增加（P<0.01）。结论：≥40岁ASD患者封堵术后左房形态及功能恢复较慢。
Abstract:
AIM:To analyze the influence of age on recovery of left atrial size and function after percutaneous closure of secundum atrial septal defect. METHODS: Forty-nine adult patients were divided into two groups: group A (23 patients), 13 males and 10 females aged from 20-38(31±12) years and group B (26 patients), 9 males and 17 females aged from 40-72(49±14) years. All patients had transthoracic echocardiogram (TTE) examination before as well as 2 days and 1, 3 and 6 months after operation to assess the diameter of left atrium and left atrial volume. RESULTS: Left atrium size in group A significantly decreased 3 months after operation compared with that before operation (P<0.05), whereas the size in group B decreased significantly 6 months after operation (P<0.05). LAVte in group A statistically reduced 2 days after operation (P<0.05), whereas in group B it did not decrease statistically until 6 months after operation (P<0.05). LAVpe reduced 3 months (P<0.05) and 6 months (P<0.01) after operation, whereas LAEF increased 1 month (P<0.01) and 3 months (P<0.01) after operation in respective group. CONCLUSION: Recovery of size and function of left atrium patients with ASD who were ≥40 years after percutaneous closure is slower compared with that in younger patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2011-08-07.通讯作者：张玉顺，教授，主要从事先天性心脏病的介入治疗的研究Email:zys2889@sina.com 作者简介：李伟，医师，硕士 Email:mynewlife@stu.xjtu.edu.cn
更新日期/Last Update: 2012-04-01