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|本期目录/Table of Contents|

钙信号调节异常在房颤电重构过程中的作用(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2012年第2期
页码:
267-270
栏目:
综述
出版日期:
2012-04-25

文章信息/Info

Title:
Role of calcium management abnormalities during electrical remodeling in progression of atrial fibrillation
作者:
钱海超; 张鹤萍 综述; 吴永全; 严松彪 审校
(首都医科大学附属北京友谊医院心内科，北京 100050)
Author(s):
QIAN Hai-chao;  ZHANG He-ping;  WU Yong-quan;  YAN Song-biao
(Department of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, Beijing, China)
关键词:
心房颤动; 钙超载; 钙泄漏
Keywords:
atrial fibrillation;  calcium overload;  calcium leak
分类号:
R541.75
DOI:
-
文献标识码:
A
摘要:
心房颤动（AF）是一种多因素导致的疾病，持续性AF后期不可避免要有结构上出现相应的改变，故在早期电重构期进行针对性的治疗很有必要。本文主要从AF电重构产生的生理基础、AF患者钙信号的改变及AF药物治疗的新思想方面做一综述。
Abstract:
Atrial fibrillation (AF) is a multifactorial disease and the mechanisms that underlie AF are various. Long-term persistence of AF unavoidably causes structural remodeling changes; therefore, it is crucial to treat early electrical atrial remodeling as a target in anti-AF therapy. Here we reviewed the physiological bases of electrical atrial remodeling, the unique features of atrial intracellular Ca2+ management in AF patients and the novel medical treatments for AF.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2011-09-20.通讯作者：吴永全，主任医师，主要从事心律失常的诊断与治疗研究 Email:wuyongquan1@yahoo.com.cn 作者简介：钱海超，硕士生 Email:xiaoxiaoyuxie1986122@126.com
更新日期/Last Update: 2012-04-01