急性冠脉综合征并发糖尿病患者GRACE评分的临床意义
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2013年第1期
- 页码:
- 51-053
- 栏目:
- 临床研究
- 出版日期:
- 2013-02-25
文章信息/Info
- Title:
- GRACE scores and prognosis in patients with acute coronary syndrome complicated by diabetes
- Author(s):
- QIU Rong; LI Xueling; LI Qun
- (Department of Cardiovascular Medicine, Fengtai Hospital, Beijing 100071, China)
- 关键词:
- 急性冠脉综合征; 冠脉造影; 危险评分; 全球急性冠状动脉事件注册; 糖尿病
- Keywords:
- acute coronary syndrome; coronary angiography; risk score; global registry of acute coronary events; diabetes mellitus
- 分类号:
- R514.4
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的:评价全球急性冠状动脉事件注册（GRACE）评分对急性冠脉综合征(ACS)患者冠状动脉病变及预后的预测价值。方法： 收集2007年1月~2009年12月在我院住院的ACS患者212例，行GRACE危险评分并行冠状动脉造影，分析不同组别的冠状动脉造影特点、糖尿病与GRACE评分的关系以及6个月终点事件的发生率。结果： 低、中、高危3组患者冠状动脉病变血管支数和病变严重程度的GRACE评分差异具有统计学意义（P<005或P<001）。糖尿病组和非糖尿病组的GRACE评分差异有统计学意义（P<005）。GRACE评分低、中、高危3组终点事件发生率依次有所增高，但差异未达到显著水平。糖尿病组与非糖尿病组的终点事件发生率差异无统计学意义。结论： GRACE评分对冠状动脉病变判定有一定价值，糖尿病患者GRACE评分高危组占较大比例。
- Abstract:
- AIM:To evaluate value of the Global Registry of Acute Coronary Events (GRACE) scores for acute coronary syndrome (ACS) and prognostic prediction. METHODS: GRACE risk scores were graded and coronary artery angiography was performed in 212 hospitalized patients at our department between January 2007 and December 2009. Angiographic characteristics, the relationship between diabetes and GRACE scores and the incidence rate of 6month end event in different groups were analyzed. RESULTS: Significant differences of GRACE scores were observed in the number of pathological coronary arteries and the severity of lesions (P<005, P<001). No significant differences were observed in the incidence rate of 6month end event among the low, medium and highrisk groups. No significant differences were seen in the incidence rate of 6month end event between the groups with diabetes and without diabetes. CONCLUSION: GRACE scoring system has some predictive value with regard to the severity of lesions and the prognostic assessment of patients with coronary artery disease. Highrisk group accounts for a large proportion in patients with diabetes.
参考文献/References
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[2]Granger CB,Goldberg RJ,Dabbous OH,et al.For the global registry of acute coronary events investigation .Predictors of hospital mortality in the global registry of acute coronary events[J].Arch Intern Med,2003,163(19):2345.
[3]霍 勇.伴随循证医学走入真实世界——GRACE研究给我们的提示[J].中华医学信息导报,2002,17(11):12-13.
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[5]Sean M,Garrick C,Carolyn H,et al.Diabetes and mortality following acute coronary syndromes[J].JAMA,2007,298(7):765-775.
[6]苏 工,米树华,杨红霞,等.动态监测老年糖尿病急性冠脉综合征患者急性期血糖波动的变化及意义[J].中国全科医学,2010,13(27):3011-3014.
[7]田声放,孙元芬,潘巍巍,等.老年急性冠状动脉综合征合并糖尿病患者介入治疗的疗效和预后[J].中华老年心血管病杂志,2009,11(11):837-839.
备注/Memo
- 备注/Memo:
- 收稿日期：2012-07-06.作者简介：邱蓉，主治医师，硕士Email：longgegema@gmail.com
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