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|本期目录/Table of Contents|

心肌细胞的核质网

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第4期
页码:
499-502
栏目:
综述
出版日期:
2013-07-25

文章信息/Info

Title:
Nucleoplasmic reticulum in cardiomyocytes
作者:
常 惠; 余志斌
(第四军医大学航空航天医学教育部重点实验室、航空航天生理学教研室，陕西 西安 710032)
Author(s):
CHANG Hui;  YU Zhi-bin
(Key Laboratory of Aerospace Medicine & Department of Aerospace Physiology, Fourth Military Medical University, Xi’an 710032, Shaanxi, China)
关键词:
心肌细胞; 核质网; 核钙信号; 兴奋-转录偶联; 核骨架
Keywords:
cardiomyocyte;  nucleoplasmic reticulum;  nuclear calcium signaling;  excitation-transcription coupling;  nucleoskeleton
分类号:
R337.2
DOI:
-
文献标识码:
A
摘要:
核内外膜、核孔复合体、核膜整合蛋白与核膜下紧密连接的核纤层蛋白，在细胞核内形成网状的核质网（nucleoplasmic reticulum，NR）。NR作为独立的功能单元，其不仅是包裹核质的膜结构，以维持核内环境的相对稳定性，而且还具有其他多种重要功能。本文就NR的结构、功能及其在心肌系统中发挥的作用作一简要综述。
Abstract:
The nucleoplasmic reticulum (NR) is a widespread intranuclear network comprising the nuclear envelope ［the inner (INM) and outer nuclear membranes (ONM)］, the nuclear pore complexes (NPCs), the integral membrane proteins, and the lamina rich in intermediate filament proteins underlying the INM. Therefore, the NR is not only a nuclear boundary, but also an independently functional unit. This article briefly overview the NR structure, function and role to play in the cardiac system.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2012-11-28.基金项目：国家自然科学基金课题资助(31200862) 通讯作者：余志斌，教授，主要从事重力与应用心血管生理学研究 Email:yuzhib@fmmu.edu.cn 作者简介：常惠，讲师，博士生 Email: changhui1983623@163.com
更新日期/Last Update: 2013-07-29