钙摄入与心血管疾病风险的研究进展
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2014年第2期
- 页码:
- 218-221
- 栏目:
- 综述
- 出版日期:
- 2014-01-20
文章信息/Info
- Title:
- Advances in research of calcium intake and cardiovascular diseases
- Author(s):
- WANG Jin-xi; LI Hong-wei
- (Cardiovascular Center of Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
- Keywords:
- dietary calcium; calcium supplements; cardiovascular disease
- 分类号:
- Q582；R714.252
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 钙摄入对于心血管系统的健康效应正日益受到争议。尽管早期研究提示钙质可能具有心血管系统保护作用，日益增多的证据支持过量摄入膳食钙及补充钙剂可能对心血管系统产生不利影响。钙可通过上调肾素-血管紧张素-醛固酮系统、促进血管钙化、导致短期内血钙波动、引发高凝状态等多种机制影响心血管系统。钙对于心血管系统的潜在获益与风险亟需大规模试验进一步深入评估。
- Abstract:
- The health effects of calcium intake on the cardiovascular system have become increasingly contentious. Despite some earlier studies suggesting a protective role of calcium against cardiovascular diseases, there is increasing evidence supporting the notion that excess dietary calcium and calcium supplements may have adverse effects on the cardiovascular system with the underlying mechanisms of upregulation of the renin-angiotensin-aldosterone system, vascular calcification, rise of serum calcium and hypercoagulability. The benefits and risks of calcium intake on the cardiovascular system remain to be further investigated.
参考文献/References
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备注/Memo
- 备注/Memo:
- 收稿日期：2013-06-28.
通讯作者：李虹伟，主任医师，主要从事糖代谢与心血管疾病关系研究 Email：mcw19656@gmail.com
作者简介：王锦溪，硕士生Email：wxslbz@163.com
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