血小板聚集功能监测现状
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2014年第4期
- 页码:
- 494-F004
- 栏目:
- 综述
- 出版日期:
- 2014-04-25
文章信息/Info
- Title:
- Current status of research on monitoring of platelet aggregation function
- Author(s):
- CUI Mei-hong; WEI Yu-jie; LIU Hui-liang
- （Department of Cardiology, General Hospital, Armed Police Forces, Beijing 10039, China）
- 分类号:
- R331.143
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 抗血小板药物存在很大的个体差异性，一部分患者接受抗血小板药物治疗后，仍然存在血小板高反应性(HPR)，而HPR跟不良临床结果相关。因此，学者们提出，运用血小板聚集功能监测来指导抗血小板治疗，并开展了许多关于这方面的研究，但却得出两个相悖的结论。为此，未来还需要设计更完善的研究来验证血小板功能检测的临床意义。
- Abstract:
- The platelet inhibitory effect of antiplatelet agents varies widely among individuals. Some of the patients receiving antiplatelet drugs still have high platelet reactivity and high platelet reactivity is associated with adverse clinical outcomes. Platelet aggregation function monitoring has been proposed to guide antiplatelet therapy. In recent years, research has been performed to evaluate the clinical impact of more intensive antiplatelet therapy based on platelet reactivity testing, but two opposite conclusions have been drawn. Better research should be designed to verify the clinical significance of platelet function testing.
参考文献/References
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备注/Memo
- 备注/Memo:
- 收稿日期：2013-12-25.通讯作者：刘惠亮，主任医师，主要从事心血管介入研究 Email：huiliangl531@163.com 作者简介：崔美红，硕士生 Email：cuimeihong2010@126.com
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