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|本期目录/Table of Contents|

两个年龄段急性心肌梗死患者临床特征的比较

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2014年第5期
页码:
554-557
栏目:
临床研究
出版日期:
2014-05-25

文章信息/Info

Title:
Comparison of risk factors and severity of coronary artery stenosis in acute myocardial infarction patients younger than 60 years and older than 60 years
作者:
魏钟海; 宋 杰; 徐 标
(南京大学医学院附属鼓楼医院心内科，江苏 南京 210008)
Author(s):
WEI Zhong-hai;  SONG Jie;  XU Biao
(Department of Cardiology, Drum Tower Hospital, Medical School, Nanjing University, Nanjing 210008, Jiangsu, China)
关键词:
心肌梗死; 急性; 危险因素; 年龄; 对比
Keywords:
acute myocardial infarction;  risk factor;  coronary artery;  age;  comparison
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:比较<60岁及≥60岁急性心肌梗死(AMI)患者的临床特征。方法: 回顾分析2012年8月~2013年8月因AMI在我院心脏科住院患者200例，将其分为<60岁和≥60岁两个年龄组，比较两组患者的冠心病危险因素、临床化验指标、左室收缩功能、冠脉病变的严重程度（改良Gensini评分等）。结果: <60岁组患者中男性比例、吸烟者比例、高脂血症患者以及阳性家族史比例更高（P<0.05或P<0.01），而高血压病患者、脑梗死患者比例低于≥60岁组（P<0.01）。临床检验发现<60岁组患者肾小球滤过率（eGFR）、三酰甘油（TG）、总胆固醇（TC）、载脂蛋白B（ApoB）均显著高于≥60岁组患者(P<0.01)。<60岁和≥60岁AMI患者冠脉造影结果比较发现前者单支病变比例更高（P<0.05），而后者三支病变比例更高（P<0.01）。前者改良的Gensini评分显著低于后者（P<0.05）。结论: <60岁和≥60岁AMI患者的传统冠心病危险因素、临床检查指标以及冠脉病变特点均有显著不同。
Abstract:
AIM:To compare the risk factors and severity of coronary artery lesions in patients with acute myocardial infarction (AMI) aged <60 years and >60 years. METHODS: We analyzed 200 patients with AMI admitted in our hospital from August 2012 to August 2013 retrospectively. Patients were divided into two groups: 1) aged <60 years and 2) >60 years. Risk factors, clinical test results, cardiac functions and modified Gensini scores of coronary angiography were compared between groups. RESULTS: The rates of smoking, male lipid disorder and positive family history were higher in the group <60 years of age (P<0.05 or P<0.01), whereas the rates of hypertension and stroke were lower (P<0.01). Clinical tests revealed that estimated glomerular filtration rate (eGFR), triglycerides (TG), total cholesterol (TC) and apolipoprotein B (ApoB) were significantly higher in the <60-year-old group (P<0.01). Coronary artery angiography reported a higher proportion of single vessel disease and a lower proportion of triple vessel disease in the group of <60 years of age (P<0.05 or P<0.01). The modified Gensini score was significantly lower in the group <60 years of age compared with that in the group >60 years of age. CONCLUSION: Risk factors, clinical profile and coronary artery angiography findings are different between patients <60 years and >60 years.

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备注/Memo

备注/Memo:
收稿日期：2013-12-12.
通讯作者：徐标，主任医师，主要从事冠心病介入治疗研究 Email：xubiao@medmail.com.cn
作者简介：魏钟海， 主治医师，硕士 Email：weizhnjjs@hotmail.com
更新日期/Last Update: 2014-06-05