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|本期目录/Table of Contents|

冠状动脉慢血流与肾小球滤过率降低有关联

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第1期
页码:
73-075
栏目:
临床研究
出版日期:
2014-09-25

文章信息/Info

Title:
Association between glomerular filtration rate and coronary slow flow in patients with mild renal impairment
作者:
徐海祥; 刘庆军; 钱剑峰; 潘 文; 刘 峰
(昆山市中医医院心内科，江苏 昆山 215300)
Author(s):
XU Hai-xiang;  LIU Qing-jun;  QIAN Jian-feng;  PAN Wen;  LIU Feng
(Department of Cardiology, Kunshan Hospital of TCM, Kunshan 215300, Jiangsu, China)
关键词:
冠脉慢血流; 肾功能; 肾小球滤过率; 尿酸
Keywords:
coronary slow flow;  renal function;  glomerular filtration rate;  uric acid
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:观察和分析冠脉慢血流与肾小球滤过率的关系。方法： 入选50例冠脉造影为慢血流患者组以及51例正常对照组，运用简化肾脏病膳食改良试验评估肾功能。结果： 冠脉慢血流组的肾小球滤过率显著降低，尿酸水平较高。经回归分析，尿酸（OR 1.007，95%CI 1.0-1.013，P=0.038）、肾小球滤过率（OR 0.968，95%CI 0.938-0.999，P=0.045）和吸烟（OR 3.513，95%CI 1.135-10.869，P=0.029）为冠脉慢血流独立相关因子。结论： 冠脉慢血流与肾小球滤过率有关联。
Abstract:
AIM:To evaluate the association between estimated glomerular filtration rate (eGFR) and coronary slow flow (CSF) in patients with normal to mildly impaired renal function. METHODS: Fifty patients with angiographically proven CSF and 51 controls were enrolled in this study. Modification of diet in renal disease equation was used to assess the eGFR. RESULTS: eGFR rate was mildly decreased and serum uric acid levels in the CSF group were higher. Patients with mildly impaired renal function had higher thrombolysis in myocardial infarction frame counts in three major coronary arteries. Logistic regression analysis showed that uric acid (OR 1.007, 95% CI 1.0-1.013, P=0.038), eGFR (OR 0.968, 95% CI 0.938-0.999, P=0.045) and smoking (OR 3.513, 95% CI 1.135-10.869, P=0.029) were independent risk factors for CSF. CONCLUSION: eGFR is significantly correlated with CSF in patients with normal to mildly impaired renal function.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2014-05-20.
通讯作者：刘峰，副主任医师，主要从事心血管介入诊疗研究Email：Liufeng@kstcm.org.cn
作者简介：徐海祥，主治医师，硕士Email：doctorxhx@126.com
更新日期/Last Update: 2015-01-20