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|本期目录/Table of Contents|

冠心病患者血尿酸及同型半胱氨酸水平与冠脉病变严重程度的关系

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第3期
页码:
330-331,334
栏目:
临床研究
出版日期:
2015-01-11

文章信息/Info

Title:
Relationship between blood uric acid and homocysteine and severity of coronary artery lesion
作者:
陆文林; 赵领会; 郭维军; 严士荣
（淮安市淮阴医院心内科，江苏 淮安 223300）
Author(s):
LU Wen-lin;  ZHAO Ling-hui;  GUO Wei-jun;  YAN Shi-rong
(Department of Cardiology, Huaiyin Hospital, Huaian 223300, Jiangsu, China)
关键词:
冠状动脉疾病; 血清尿酸; 同型半胱氨酸浓度; Gensini评分
Keywords:
Coronary disease;  blood uric acid;  serum homocysteine;  Gensini score
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:观察分析冠心病患者血清尿酸（UA）及同型半胱氨酸水平（homocysteine，Hcy）与冠状动脉病变程度的关系及其临床意义。方法:回顾性分析我院经冠状动脉造影诊断冠心病患者165例，按Gensini评分分为3组，A组（<20分组）、B组（20~40分组）、C组（>40分组），另将冠状动脉造影正常的54例患者作为正常对照组。分别比较各组间UA、Hcy水平。结果:冠心病患者的UA、Hcy的水平显著高于正常对照组（P<0.05），且不同Gensini积分组C组与A和B组UA、Hcy水平之间差异也有统计学意义（P<0.05）。结论:UA、Hcy水平与冠脉病变严重程度密切相关。
Abstract:
AIM:To investigate the relations between the levels of blood uric acid (UA) and serum homocysteine (HCY) and the severity of coronary artery lesions in patients with coronary heart disease (CHD). METHODS: Patients were divided into CHD group (165 cases) and normal control group (54 cases) depending on the results of the coronary angiography. According to Gensini scores, we subdivided the CHD group into three groups: Group A (<20 points), Group B (20-40 points) and Group C (>40 points). The concentrations of blood uric UA and serum HCY were compared among groups. RESULTS: The levels of blood UA and serum homocysteine HCY in CHD groups were obviously higher than those in normal control group (P<0.05), with statistically significant difference between groups with different Gensini scores (P<0.05). CONCLUSION: Concentrations of blood UA and serum HCY are closely related to the severity of coronary artery lesions and can be a severity predictor of coronary artery lesions.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2014-06-21.
作者简介：陆文林，主治医师，硕士Email：kinglwl@126.com
更新日期/Last Update: 2015-02-03