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|本期目录/Table of Contents|

影响急性ST段抬高型心肌梗死患者入院时心功能的危险因素分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第6期
页码:
683-686
栏目:
临床研究
出版日期:
2015-07-15

文章信息/Info

Title:
Multivariate logistic regression analysis of risk factors for heart function of patients with acute ST segment elevation myocardial infarction
作者:
李 军
(自贡市第三人民医院心血管内科，四川 自贡 643020)
Author(s):
LI Jun
(Department of Cardiology, Zigong Third People's Hospital, Zigong 643020, Sichuan, China)
关键词:
心肌梗死; 急性; ST段抬高; 心功能; 危险因素; 心力衰竭
Keywords:
acute ST segment elevation myocardial infarction;  cardiac function;  risk factors;  heart failure
分类号:
R541.4;R541.61
DOI:
-
文献标识码:
A
摘要:
目的 分析影响急性ST段抬高型心肌梗死(STEMI)患者入院时心功能的危险因素。方法 将145例STEMI患者按入院时心功能分级分为心功能正常组（n=95）与心功能异常组（n=50），分别采用单因素分析与多元Logistic回归分析的方法对影响STEMI患者入院时心功能的危险因素进行分析。结果 ①经单因素分析，心功能正常组与心功能异常组在年龄、糖尿病、入院心率、舒张压、β-受体阻滞剂及IL-6水平方面的差异均具有统计学意义（P<0.05或P<0.01）；②将上述经单因素分析具有统计学意义的因素进行赋值并带入至多元Logistic回归模型之中，最终确定影响STEMI患者入院时心功能的独立危险因素为：年龄（P<0.05，OR=1.83，95%CI为1.36-2.21）、糖尿病（P<0.05，OR=2.24，95%CI为1.83-3.11）、入院心率（P<0.05，OR=2.37，95%CI为1.40-4.16）、舒张压（P<0.05，OR=2.59，95%CI为2.21-3.39）及IL-6水平（P<0.05，OR=3.02，95%CI为2.87-4.16）。结论 年龄、糖尿病、入院心率、舒张压及IL-6水平为影响STEMI患者入院时心功能的独立危险因素。
Abstract:
AIM We used multivariate logistic regression analysis of risk factors for heart function of patients with acute ST segment elevation myocardial infarction (STEMI) to provide a basis for clinical prediction of STEMI patients complicated with heart failure. METHODS One hundred forty five patients with STEMI were divided into normal heart function group (n=95) and abnormal cardiac function group (n=50), and risk factors for heart function of patients with acute STEMI were analyzed by univariate Pearson and multivariate logistic regression analysis. RESULTS 1) Using Pearson single factor analysis, the difference of normal heart function group and abnormal heart function groups according to age, diabetes, admission heart rate and diastolic blood pressure, beta blockers and IL-6 levels were statistically significant (P<0.05-0.01). 2) Pearson single factor analysis was statistically significant and brought into multivariate logistic regression model, finally determining the effects of STEMI on admission in patients with risk factors for heart function: age (β=0.419, SE=0.192, Wald=8.293, P<0.05, OR=1.827, 95%CI, 1.362-2.209), diabetes mellitus (β=0.753, SE=0.368, Wald=9.091, P<0.05, OR=2.238, 95%CI 1.827-3.114), admission heart rate (β=0.746, SE=0.273, Wald=7.082, P<0.05, OR=2.372, 95%CI, 1.402-4.156), diastolic blood pressure (β=0.810, SE=0.556, Wald=10.281, P<0.05, OR=2.591, 95%CI, 2.211-3.391) and IL-6 (β=0.627, SE=0.431, Wald=14.382, P<0.05, OR=3.021, 95%CI 2.873-4.159). CONCLUSION Age, diabetes mellitus, admission heart rate, diastolic blood pressure and IL-6 level of risk of cardiac function in STEMI patients on admission are factors affecting STEMI patients complicated with heart failure and provide some basis for the diagnosis and treatment of STEMI patients complicated with heart failure.

参考文献/References

[1]史云桃,蒋廷波.急性ST段抬高心肌梗死患者合并心力衰竭的危险因素分析[J].中华老年心脑血管病杂志,2014,16(2):151-154.
[2]吴学思.优化药物治疗对慢性心力衰竭的重要性[J].中华老年心脑血管病杂志,2014,18(16):2-3.
[3]孙路路，吕蓉，梁 涛，等.心力衰竭患者出院后1年内预后状况及影响因素[J].中国循环杂志,2013,2(28):125-128.
[4]Miyagi M,Ishii H,Murakami R,et al.Impact of long-term statin treatment on coronary plaque composition at angiographically severe lesions:a nonrandomized study of the history of long-term statin treatment before coronary angioplasty[J]. Clin Thera,2009,31(1):64-73.
[5]韩瑞梅.不同剂量阿托伐他汀对急性ST段抬高心肌梗死患者心功能的影响[J].中国基层医药,2011,18(24):3340-3341.
[6]Stebbins A,Mehta RH,Armstrong PW,et al.Assessment of Pexelizumabin Acute Myocardial Infarction(APEX AMI Investigators).A model for predicting mortality in acute ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention:resuits from the Asessment of Pexelizumab in Acute Myocardial Infarction Trial[J].Cire Cardiovasc Interv,2010,3(5):414-422.
[7]Savic L,Mrdovic I,Peranieic J,et al.Prognostic significance of the occulTence of acute heart failure after successful primary pe reutaneous coronary intervention[J].J Invasive Cardiol,2010,22(7):307-311.
[8]张晓雷，王荣英，田英平，等.急性ST抬高心肌梗死心电图心肌缺血分级的临床意义[J].临床荟萃,2012,27(12):1018-1020.
[9]Szummer K,Lundman P,Jacobsen SH,et al.Relation between rehal function, presentation,use of therapies and in-hospital complicationsin acute coronary syndrome: data from the SWEDEHEART register[J].J Intern Med,2010,268(1):40-49.
[10]王荣英，田英平，张晓雷，等.急性ST段抬高心肌梗死QRS波群形态对溶栓后心功能及预后的影响[J].中国循环杂志,2009,24(2):134-136.

备注/Memo

备注/Memo:
收稿日期：2014-09-17.
作者简介：李军，主治医师 Email：919701973@qq.com
更新日期/Last Update: 2015-07-23