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|本期目录/Table of Contents|

扩张型心肌病患者校正QT间期与左室收缩功能的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第1期
页码:
40-042
栏目:
临床研究
出版日期:
2015-09-15

文章信息/Info

Title:
Relationship between QTc interval and left ventricular systolic functions in patients with dilated cardiomyopathy
作者:
贾秋蕾1; 2; 褚瑜光1; 胡元会1;  杜 柏1; 魏 艺1; 师 帅1
(1.中国中医科学院广安门医院心内科，北京 100053；2.北京中医药大学，北京 100029）
Author(s):
JIA Qiu-lei1; 2;  CHU Yu-guang1;  HU Yuan-hui1;  DU Bai1;  WEI Yi1;  SHI Shuai1
(1.Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China；
2.Beijing University of Chinese Medicine, Beijing 100029, China)
关键词:
扩张型心肌病; 校正QT间期：左室收缩功能
Keywords:
dilated cardiomyopathy;  QTc interval;  left verntricular systolic function
分类号:
R542.2
DOI:
-
文献标识码:
A
摘要:
目的 探讨扩张型心肌病（DCM）患者校正QT（QTc）间期与心功能的关系。方法 选择2004年1月~2014年6月入住中国中医科学院广安门医院的103例DCM患者，根据心电图QTc时限分为QTc间期>440 ms组59例，QTc间期≤440 ms组44例，比较其心脏结构和功能的差异。结果 QTc>440 ms组患者左室收缩末期内径（LVESD）、左室舒张末期内径（LVEDD）显著大于QTc≤440 ms组（均P<0.05）；QTc>440 ms组患者左室射血分数（LVEF）、左心室短轴缩短率（FS）显著小于QTc≤440 ms组（均P<0.01）。LVESD、LVEDD与QTc间期呈正相关（r=0.261，P<0.01、r=0.252，P<0.05）； LVEF、FS与QTc间期呈负相关（r=-0.275，P<0.01、r=-0.304，P<0.01）。结论 DCM患者QTc 间期与左室内径以及收缩功能存在相关性。
Abstract:
AIM To examine the relationship between QTc interval and cardiac functions in patients with dilated cardiomyopathy (DCM). METHODSOne hundred and three patients with DCM were divided into two groups according to QTc interval in ECG: QTc interval>440 ms group (n=59) and QTc interval 440 ms group (n=44). Cardiac structure and functions were determined by echocardiogram and were compared. RESULTSLVSDD and LVEDD in QTc interval>440 ms group were significantly higher than those in QTc interval 440 ms group (both P<0.05). EF and FS in QTc interval>440 ms group were significantly lower than those in QTc interval 440 ms group (both P<0.01). LVSSD and LVEDD were positively related to QTc interval (r=0.261, P<0.05; r=0.252, P<0.05). EF and FS were negatively related to QTc interval (r=-0.275, P<0.01; r=-0.304, P<0.01). CONCLUSIONQTc interval is related to LVSDD, LVEDD and left ventricular systolic functions. QTc interval can be used as an evaluation marker of cardiac functions in patients with DCM.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2015-01-18.
通讯作者：胡元会，主任医师，主要从事中医药治疗心血管疾病研究 Email:huiyuhui55@sohu.com
作者简介：贾秋蕾，硕士生 Email:lotusrosa@163.com
更新日期/Last Update: 2015-09-16