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乌鲁木齐市健康体检人群非酒精性脂肪肝的分布特征以及与代谢综合征及其各组分的关联性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第2期
页码:
175-178
栏目:
临床研究
出版日期:
2015-11-25

文章信息/Info

Title:
Distribution of nonalcoholic fatty liver disease and the association between NAFLD and metabolic syndrome and components of the Urumqi health check-up population
作者:
程志琴高 颖陈 丹赵卫云
(新疆医科大学第一附属医院干部病房内二科,新疆 乌鲁木齐 830011)
Author(s):
CHENG Zhi-qin GAO Ying CHEN Dan ZHAO Wei-yun
(Department of Internal Medicine, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, Xinjiang, China)
关键词:
非酒精性脂肪肝代谢综合征汉族维族哈族回族
Keywords:
non-alcoholic fatty liver disease metabolic syndrome Han Uyghur Kazak Hui
分类号:
R575.5
DOI:
-
文献标识码:
A
摘要:
目的 分析乌鲁木齐市健康查体人群非酒精性脂肪肝(NAFLD)的分布特征以及与代谢综合征及其各组分的关联性。方法 以新疆医科大学第一附属医院体检中心7 913例健康体检者为研究对象,完成身高、体质量、腰围、血脂、血压、血糖、血尿酸、腹部B超等项目检查,观察NAFLD与代谢综合征及其组分的关系。结果 乌鲁木齐市人群NAFLD患病率为31%,其中男性患病率为41%,女性患病率为19%,两者比较差异有显著性意义(P<0.05);汉族、维吾尔族、哈萨克族、回族人群非酒精性脂肪肝患病率分别为30%、40%、31%、33%。NAFLD组中肥胖症、血脂紊乱、糖尿病的患病率显著高于非NAFLD组(P<0.05)。结论 ①人群NAFLD的男性患病率高于女性;②NAFLD与代谢综合征及其组份具有关联性。
Abstract:
AIM To analysis the distribution of nonalcoholic fatty liver disease (NAFLD) and the association between NAFLD and metabolic syndrome (MetS) and components of the Urumqi health check-up population. METHODS By completing research on height, body mass index (BMI), waist circumference, blood lipids, blood glucose, blood pressure, blood uric acid and abdominal ultrasound of 7913 cases in the Medical Center of the First Teaching Hospital of Xinjiang, this study observes the relationship between NAFLD and MetS and its components. RESULTS According to the research, first, the population prevalence of NAFLD in Urumqi was 31% including 41% of male prevalence and 19% of female prevalence, the two comparative differences were significant (P<0.05). Second, among Hans, Uyghurs, Kazaks and Huis, the prevalence of NAFLD, respectively, were 30%, 40%, 31% and 40%. Third, in the NAFLD group, the prevalence of obesity, dyslipidemia, and diabetes was significantly higher than in the non-NAFLD group (P<0.05). CONCLUSION Prevalence of NAFLD in males is higher than in females. MetS and its components are associated with NAFLD.

参考文献/References

[1]中华医学会肝病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南(2010年修订版)[J].中华肝脏病杂志,2010,18(3):163-166.
[2]中华医学会糖尿嫡学分会代谢综合征研究协作组.中华医学会糖尿病学分会关于代谢综合征的建议[J].中华糖尿病杂志,2004,12(3):156-161.
[3]非酒精性脂肪性肝病的流行现状及自然病程调查[J].广东医学,2010,31(21):2850-2852.
[4]杨兴祥,刘玉萍,戴 敏,等.成都市健康体检成人非酒精性脂肪肝流行病学研究[J].中华健康管理学杂志,2010,4(1):22-24.
[5]范建高,朱 军,李新建,等.上海市成人脂肪肝患病率及其危险因素流行病学调查[J].中华肝脏病杂志,2005,13(2):83-88.
[6]陈 曦,范建高.非酒精性脂肪肝:代谢综合征的另一个特征[J].实用肝脏病杂志,2004,7(1):19-21.

备注/Memo

备注/Memo:
收稿日期:2014-11-30.
基金项目:新疆维吾尔自治区科技计划项目资金资助(201554141)
通讯作者:高颖,主任医师,主要从事心血管内科疾病诊疗研究 Email:sunflowergaoying@163.com
作者简介:程志琴,硕士生 Email:biansan0330@163.com
更新日期/Last Update: 2016-04-25