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Title:: Clinical effect of fast diet on patients with impaired glucose tolerance

Author(s):: ZHANG Ming-guo; CHU Tian-shu; ZHU Guo-fu; RUAN Zhi-min; WU Li-yong; ZHANG Ran; ZHANG Qian; (Department of Cardiology, Second Affiliated Hospital, Kunming Medical University, Kunming 650101, Yunnan, China)

摘要:: 目的观察轻断食治疗糖耐量异常患者的临床效果。方法将糖耐量异常患者120例，随机均分为轻断食组和阿卡波糖组（每组n=60）。轻断食组应用轻断食方法进行治疗,阿卡波糖组应用阿卡波糖进行治疗。治疗6个月后，比较两组患者各项临床指标的改善情况。结果 2组患者接受治疗后，较本组治疗前三酰甘油(TG)、空腹血糖(FPG)和餐后2 h血糖(P2hPG)均显著降低(P<0.01)；轻断食组总胆固醇(TC)治疗后较治疗前显著降低,而阿卡波糖组治疗前后TC并无显著差异。两组治疗前TC无显著差异,而治疗后轻断食组TC显著低于阿卡波糖组(P<0.01)。结论糖耐量异常患者应用轻断食疗法能够收到较好的临床治疗效果。

Abstract:: AIM To investigate the clinical effect of the treatment of the fast diet on patients with impaired glucose tolerance (IGT). METHODS One hundred and twenty patients with IGT were randomly divided into group A (n=60) and group B (n=60). Group A was treated with the fast diet and group B with acarbose tablets. After 6 omonths of treatment, the clinical indexes of the two groups were analyzed. RESULTS After treatment, levels of TG, FPG and P2hPG in both groups decreased (all P<0.01); however, there was a statistically significant difference in TC level between groups (Group A, P<0.01). CONCLUSION Treatment with fast diet is clinically effective in patients with IGT.