我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

扩张性心肌病患者左室射血分数与胆固醇水平的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第3期
页码:
293-295
栏目:
临床研究
出版日期:
2016-01-05

文章信息/Info

Title:
Correlation between left ventricular ejection fraction and total cholesterol in dilated cardiomyopathy
作者:
师 帅褚瑜光胡元会贾秋蕾魏 艺张菀桐
(中国中医科学院广安门医院心内科,北京 100053)
Author(s):
SHI Shuai CHU Yu-guang HU Yuan-hui JIA Qiu-lei WEI Yi ZHANG Wan-tong
(Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China)
关键词:
心肌病扩张性左室射血分数总胆固醇
Keywords:
dilated cardiomyopathy left ventricular ejection fraction total cholesterol
分类号:
R542.2
DOI:
-
文献标识码:
A
摘要:
目的 分析扩张性心肌病(DCM)患者左室射血分数(LVEF)与血清总胆固醇(TC)的关系。方法 选取住院DCM患者123例,分为LVEF>40%组(34例)和 LVEF≤40%组(89例)。入院后收集患者一般情况及测定血液生化,以超声心动图检查患者的心脏功能及结构,并进行比较。结果 LVEF>40%组与LVEF≤40%患者比较:LVEF>40%组年龄小于LVEF≤40%组(P<0.05);LVEF>40%组TC显著高于LVEF≤40%组(P<0.05)。TC与LVEF呈正相关(r=0.287,P<0.01)。结论 DCM患者LVEF与TC有相关性。
Abstract:
AIM To investigate the correlation between left ventricular ejection fraction and serum total cholesterol in patients with dilated cardiomyopathy (DCM) and to provide an index for the emergence of heart failure. METHODSOne hundred and twenty-three patients with dilated cardiomyopathy were divided into two groups: LVEF >40% group (n=34) and LVEF ≤40% group (n=89). General information and biochemical data of serum were collected, and the cardiac structure and functions were determined by echocardiogram and compared. RESULTSPatients in the LVEF>40% group were younger than LVEF≤40% group (P<0.05). Total cholesterol in LVEF>40% group was significantly higher than in LVEF≤40% group (P<0.05). Total cholesterol was positively related to LVEF (r=0.287, P<0.01). CONCLUSIONTotal cholesterol may serve as a helpful predictor of heart failure.

参考文献/References

[1]Giannessi D,Maltinti M,Del Ry S.Adiponectin circulating levels:A new emergingbiomarker of cardiovascular risk[J].Pharmacol Res,2007,56(6):459-467.
[2]中华医学会心血管病分会,中华心血管病杂志编委会,中国心肌病诊断与治疗建议工作组.心肌病诊断与治疗建议[J].中华心血管病杂志,2007,35(1):3-16.
[3]Francone M.Role of cardiac magnetic resonance in the evaluation of dilated cardiomyopathy: diagnostic contribution and prognostic significance[J].Radiology,2014,2014:365404.
[4]Feldman AM,Begay RL,Knezevic T,et al.Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy[J].J Cell Physiol,2014,229(11):1697-1702.
[5]Kawai C,Matsumori A.Dilated cardiomyopathy update:infectious-immune theory revisited[J].Heart Fail Rev,2013,18(6):703-714.
[6]Sandi RM,Pol KG,Basavaraj P,et al.Association of Serum Cholesterol,Triglyceride,High and Low Density Lipoprotein(HDL and LDL)Levels in Chronic Periodontitis Subjects with Risk for Cardiovascular Disease (CVD):A Cross Sectional Study[J].J Clin Diagn Res,2014,8(1):214-216.
[7]Rothnie A,Theron D,Soceneantu L,et al.The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence[J].Eur Biophys J,2001,30(6):430-442.
[8]张广伟.细胞膜胆固醇通过PKC通路调节心肌Connexin43的表达和分布[D].福建:厦门大学,2014.
[9]Granér M,Pentik?inen MO,Nyman K,et al.Cardiac steatosis in patients with dilated cardiomyopathy[J].Heart,2014,100(14):1107-1112.
[10]Giannessi D,Caselli C,Del Ry S,et al.Adiponectin is associated with abnormal lipid profile and coronary microvascular dysfunction in patients with dilated cardiomyopathy without overt heart failure[J].Metabolism,2011,60(2):227-233.
[11]郭勇娟.扩张型心肌病患者血脂与血尿酸、高敏C-反应蛋白水平及心功能关系[D].浙江:浙江大学,2007.
[12]Christ M,Klima T,Grimm W,et al.Prognostic significance of serum cholesterol levels in patients with idiopathic dilated cardiomyopathy[J].Eur Heart J,2006,27(6):691-699.
[13]李鹏飞,杨 波,王 鑫,等.扩张型心肌病患者血清PAB、HDL-C、hs-CRP水平及意义[J].疑难病杂志,2011,10(1):2-4.

备注/Memo

备注/Memo:
收稿日期:2015-03-31.
通讯作者:胡元会,主任医师,主要从事中医药防治心血管疾病的研究 Email:shawshaw@126.com
作者简介:师帅,硕士生 Email:292506375@qq.com
更新日期/Last Update: 2016-01-07