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|本期目录/Table of Contents|

右心声学造影对卵圆孔未闭右向左分流的检出情况

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第3期
页码:
323-325
栏目:
临床研究
出版日期:
2016-01-05

文章信息/Info

Title:
Diagnostic value of right heart contrast echocardiography in detection of right to left shunt in patent foramen ovale
作者:
王英莉1; 张 娜2; 郭朋悦1; 张 军3; 吴利杰4
（延安大学咸阳医院：1.功能科，2.神经内科，4.心内科，陕西 咸阳 712000；
3.第四军医大学西京医院超声诊断科，陕西 西安 710032）
Author(s):
WANG Ying-li1;  ZHANG Na2;  GUO Peng-yue1;  ZHANG Jun3;  WU Li-jie4
(1.Department of Functional Examinations, 2.Neurology Department；
4.Department of Cardiology, Xianyang Hospital, Yan’an University, Xianyang 712000, Shaanxi, China；
3.Department of Diagnostic Ultrasound, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi, China)
关键词:
经胸超声心动图;  声学造影剂;  卵圆孔未闭;  右向左分流
Keywords:
transthoracic echocardiography;  ultrasound contrast agent;  patent foramen ovale;  right to left shunt
分类号:
R541.1
DOI:
-
文献标识码:
A
摘要:
目的 应用经胸超声心动图(TTE)结合经胸右心声学造影（cTTE）检查评估不明原因脑卒中患者卵圆孔未闭右向左分流发生情况。方法 连续选取不明原因脑梗死患者285例，正常人114例。所有患者均行TTE检查，后用空气加血激活的生理盐水（ASB）行cTTE检查，观察有无右向左分流(right to left shunt，RLS），并进行分级。结果 不明原因脑梗死组cTTE与正常人群组cTTE比较：RLS总阳性率51% vs. 32%（P<0.01），少量组14% vs. 10%（P>0.05），中量组6% vs. 3%（P>0.05），大量组31% vs. 19%（P<0.01）。结论 cTTE是不明原因脑梗死患者RLS有效的检查手段。
Abstract:
AIM To assess right to left shunt of patent foramen ovale (PFO) by transthoracic echocardiography (TTE) combined with right heart contrast echocardiography by chest (cTTE) in unexplained cerebral infarction patients. METHODSWe chose 285 unexplained cerebral infarction patients as observation group and 114 healthy subjects as controls. All subjects underwent TTE and then cTTE activated by ASB and atmosphere. The right to left shunt and the shunt grade were evaluated. RESULTSThe positive rate of right to left shunt in observation group and control group was 51% and 32%, respectively, with significant difference by statistical analysis (P<0.01). The positive rates of small, medium and large shunt in observation group and control group were, respectively, 14% vs. 10%, 6% vs. 3% and 31% vs. 19%. There was no statistical significance in small and medium shunt but there was a statistical difference (P<0.01) in large shunt between observation group and control group. CONCLUSIONRight to left shunt in unexplained cerebral infarction patients is significantly higher than in healthy subjects, indicating right to left shunt of PFO may be one of the core causes for cerebral infarction. cTTE is an effective method to examine right to left shunt in the unexplained cerebral infarction patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2015-06-23.
通讯作者：张军,主任医师，主要从事心血管超声研究 Email:zhangjun@fmmu.edu.cn
作者简介：王英莉，主治医师，硕士生 Email:13992013302@163.com
更新日期/Last Update: 2016-01-07