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Title:: A case-control study of H-type hypertension and stroke in Xi’an area

作者:: 车楠¹; 2; 张维璐¹; 高军宪²; 王朝侠²; 席斐³; 王安辉¹; 龙泳¹; （1.第四军医大学军队流行病学教研室，陕西西安 710032；2.西安市第九医院神经内科，陕西西安 710054；3.解放军518医院检验科，陕西西安 710043）

Author(s):: CHE Nan¹; 2; ZHANG Wei-lu¹; GAO Jun-xian²; WANG Zhao-xia²; XI Fei³; WANG An-hui¹; LONG Yong¹; (1.Department of Epidemiology, Fourth Military Medical University, Xi’an 710032, Shaanxi, China；
2.Department of Neurology, Ninth Hospital of Xi’an, Xi’an 710054, Shaanxi, China；
3.Clinical labaratory, PLA 518 Hospital, Xi’an 710043, Shaanxi, China)

关键词:: 高血压; H型; 脑卒中; 病例对照研究; 西安地区

Keywords:: hypertension; H-type; stroke; case-control study; Xi’an district

分类号:: R544.1

DOI:: -

文献标识码:: A

摘要:: 目的探讨西安地区H型高血压等相关因素与脑卒中的关系，为预防与控制措施提供理论依据。方法本研究采用病例对照的研究设计，连续收集西安市第九医院神经内科住院患者400例为研究对象，其中脑卒中患者作为病例组，非脑卒中患者作为对照组，对其一般人口学特征、家族史、吸烟史、饮酒史、高血压、H型高血压、既往病史、性格类型等与脑卒中之间的关系进行研究。数据通过SPSS18.0处理，主要采用单因素和调整因素的Logistic回归模型进行统计分析。结果单因素分析显示，高龄、男性、文化程度低、脑力劳动、吸烟、高血压、H型高血压、亲属脑卒中史、亲属心脏病史以及内向型性格等因素与西安地区脑卒中具有相关性，其中一级亲属的脑卒中和心脏病史的危险性均高于普通亲属；调整年龄性别的Logistic回归分析显示，高血压、H型高血压、一级亲属脑卒中史和心脏病史等因素与西安地区脑卒中具有相关性；在轻度脑卒中和中重度脑卒中的比较中，文化程度低、内向型性格、吸烟和高血压与中重度脑卒中具有相关性。结论高血压、H型高血压、一级亲属脑卒中史和心脏病史等因素与西安地区脑卒中的发生关系密切，高血压、文化程度低、内向型性格和吸烟与中重度脑卒中的发生相关。

Abstract:: AIM To study the relationship between H-type hypertension and stroke in Xi’an area. METHODSA case-control study was designed and 400 consecutive inpatients in the Department of Neurology, Ninth Hospital of Xi’an were enrolled. Patients were divided into two groups (case and control) according to stroke diagnosis. Data were analyzed and compared between groups including age, gender, educational level, body mass index (BMI), marital status, occupation, cigarette smoking, alcohol, diabetes mellitus, hypertension, H-type hypertension, family history of stroke, family history of heart disease, and social characteristics. RESULTSStroke was negatively correlated with older age, male gender, low educational level, intellectual occupation, cigarette smoking, hypertension, H-type hypertension, family history of stroke, and family history of heart diseases. OR values of family history of stroke and heart diseases in parents were higher than those of other relatives. Hypertension, low educational level, introversion, and cigarette smoking were correlated with moderate/severe stroke. CONCLUSIONHypertension, H-type hypertension, parental history of stroke, and parental history of heart diseases are risk factors for stroke. Low educational level, introversion, cigarette smoking, and hypertension are risk factors for moderate/severe stroke in the Xi’an area.

参考文献/References

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西安地区H型高血压等因素与脑卒中关系的病例对照研究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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