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|本期目录/Table of Contents|

PCI术后AMI患者非梗死区冠脉血流储备的变化及其对左室功能的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第1期
页码:
74-077
栏目:
临床研究
出版日期:
2016-10-05

文章信息/Info

Title:
Changes and effects of coronary flow reserve in non-infarcted myocardium after PCI
作者:
程荣超1; 朱晓明2; 李学奇1
(1.哈尔滨医科大学附属第四医院心内科,黑龙江 哈尔滨 150021；
2.黑龙江省农垦职业学院，黑龙江 哈尔滨 150000）
Author(s):
CHENG Rong-chao1;  ZHU Xiao-ming2;  LI Xue-qi1
(1.Department of Cardiology, Fourth Affiliated Hospital, Harbin Medical University, Harbin 150021, Heilongjiang, China；
2.Department of Echocardiology, Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang, China)
关键词:
心肌梗死; 急性; 微循环障碍; 左室功能
Keywords:
myocardial infarction;  microvascular dysfunction;  left ventricular function
分类号:
R445.1
DOI:
-
文献标识码:
A
摘要:
目的 观察和分析急性心肌梗死（AMI）患者PCI术后非梗死区冠脉血流储备（CFR）的变化及其对左室功能的影响。方法 22名AMI患者PCI术后1周行二维超声心动图和多巴酚丁胺负荷实时心肌声学造影（MCE）检查，测量左室功能和梗死区、非梗死区CFR，比较非梗死区CFR与梗死区及正常对照组CFR；根据非梗死区CFR值将患者分为两组，比较两组远期左室功能的变化。结果 非梗死区CFR值与正常对照组相比明显下降，非梗死区CFR与左室舒张末期容积呈负相关。结论 AMI后非梗死区心肌同样存在微循环功能障碍，非梗死区CFR值能预测AMI后远期左室功能。
Abstract:
AIM To assess the relationship of coronary flow reserve (CFR) in the non-infarcted myocardium and left ventricular functions in patients with acute myocardial infarction (AMI) undergoing coronary intervention. METHODSWe enrolled 22 AMI patients undergoing coronary intervention. CFR in the non-infarcted myocardium was compared with that in infarcted myocardium and normal myocardium by dobutamine real-time myocardial contrast echocardiography at 1 week following coronary angioplasty. Left ventricular functions were assessed by two-dimensional echocardiography. Patients were divided into two groups according to the CFR value of the non-infarcted myocardium and changes of left ventricular functions were compared between groups. RESULTSCFR value decreased in non-infarcted myocardium compared with control group. Furthermore, there was a significant negative correlation between CFR in the non-infarcted region and left ventricular end diastolic volume (LVEDV) at 6 months following coronary angioplasty. CONCLUSIONMicrovascular dysfunction is commonly observed in the non-infarcted myocardium in AMI patients. The CFR value in the non-infarcted myocardium can predict left ventricular function following AMI.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2015-11-04.
通讯作者：李学奇，主任医师，主要从事冠心病和心律失常的介入治疗 Emal:chengrong_chao@163.com
作者简介：程荣超，主治医师，博士生 Emal：zhuxiao_ming@163.com
更新日期/Last Update: 2016-10-09