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|本期目录/Table of Contents|

早期介入治疗对高危非ST段抬高型心肌梗死患者短期预后的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第2期
页码:
168-170
栏目:
临床研究
出版日期:
2016-11-25

文章信息/Info

Title:
Effect of early invasive strategy on short-term prognosis in high-risk patients with non-ST-elevation myocardial infarction
作者:
郭 欣1; 2; 王 熠2; 李 飞1
(1.第四军医大学西京医院心血管内科，陕西 西安 710032；
2. 解放军第五三一医院心血管内科，吉林 通化 134002)
Author(s):
GUO Xin1; 2;  WANG Yi2;  LI Fei1
(1.Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi, China；
2.Department of Cardiology, PLA 531 Hospital, Tonghua 134002, Jilin, China)
关键词:
心肌梗死; 非ST段抬高型; 早期介入治疗; 择期介入治疗; 主要不良心脏事件
Keywords:
myocardial infarction;  non-ST-elevation;  early invasive strategies;  selective invasive strategies;  major adverse cardiac events
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 比较早期与择期介入治疗对高危非ST段抬高型心肌梗死（NSTEMI）患者短期预后的影响。方法 纳入西京医院心血管内科行介入治疗的高危NSTEMI患者，根据手术实施时间分为早期介入组（入院24 h内）和择期介入组（24~48 h）。比较两组患者围手术期并发症、住院期间死亡、PCI成功率、住院时间以及费用，对患者随访6个月，观察再发心绞痛、因冠心病再住院 、主要心血管不良事件（MACE）的发生和左心室射血分数（LVEF）改善的情况。结果 与择期介入组比较，早期介入组围手术期并发症、住院期间死亡、PCI成功率与MACE发生率差异无统计学意义，早期介入组住院时间、住院费用、再发心绞痛及因冠心病再住院率低于择期介入组，两组LVEF均明显提高，早期介入组高于择期介入组。结论 高危NSTEMI患者早期介入治疗的短期预后优于择期介入治疗。
Abstract:
AIM To compare the effect of early and selective invasive strategy in high-risk patients with non-ST-elevation myocardial infarction (NSTEMI). METHODS High-risk patients with NSTEMI in Xijing Hospital were divided into early intervention group and selective intervention group according to surgical time. Perioperative complications, in-hospital death, length of hospital stay and hospital costs were compared between groups. Patients were followed for 6 months and the occurrence of major adverse cardiovascular events (MACE) and the change of left ventricular ejection fraction (LVEF) were also compared between groups. RESULTS No statistically significant difference was found between groups according to rates of perioperative complications, in-hospital death and successful PCI, and MACE incidence. Length of hospital stay, hospital costs and the rate of hospital readmission due to recurrent angina and coronary heart disease in early intervention group were lower than those in selective intervention group. LVEF obviously increased in both groups and LVEF in early intervention group was higher than in the selective intervention group. CONCLUSION The short-term prognosis effect of early invasive strategy in high-risk patients with non-ST-elevation myocardial infarction is better than that of selective invasive strategy.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2016-01-15.
通讯作者：李飞，副教授，主要从事冠心病基础及复杂冠脉介入治疗研究 Email:lifei01@fmmu.edu.cn
作者简介：郭欣，主治医师，硕士生 Email:guoxin0537@163.com
更新日期/Last Update: 2016-10-11