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|本期目录/Table of Contents|

心房颤动与内皮功能障碍

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第2期
页码:
230-235
栏目:
综述
出版日期:
2018-02-15

文章信息/Info

Title:
Atrial fibrillation and endothelial dysfunction
作者:
李延广 综述王玉堂 审校
(解放军总医院心血管内科,北京 100853)
Author(s):
LI Yan-guang WANG Yu-tang
(Department of Cardiology, PLA General Hospital, Beijing 100853, China)
关键词:
心房颤动内皮功能障碍内皮标记物卒中与系统栓塞风险
Keywords:
atrial fibrillation endothelial dysfunction endothelial biomarker stroke and systemic embolism risk
分类号:
R541.7
DOI:
-
文献标识码:
A
摘要:
心房颤动(AF)是临床最常见的快速型心律失常,AF患者面临较高的卒中与系统栓塞风险。AF能通过炎症反应、氧化应激、肾素-血管紧张素系统激活以及血流动力学变化等机制导致内皮功能障碍(ED)。多种内皮标记物与AF之间关系密切,ED对AF的发生、发展具有重要影响。本文旨在系统阐述AF与ED之间的关系。
Abstract:
Atrial fibrillation (AF) is the most clinically encountered arrhythmia and AF patients suffer from higher risk of stroke and systemic embolism. AF can induce endothelial dysfunction(ED) through various mechanisms, including inflammation reaction, oxidative stress, renal-angiotensin system activation and hemodynamic changes. Varieties of endothelial biomarkers are closely correlated with AF. ED can significantly affect AF's occurrence and progress. This article reviews the complex relationship between AF and ED.

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备注/Memo

备注/Memo:
收稿日期:2016-11-20.基金项目:北京市科委首都市民健康项目资助(Z141100002114050); 军队保健专项资助(11BJZ10)通讯作者:王玉堂,教授,主要从事心脏起搏与心脏电生理研究 Email:wyt301@sina.com 作者简介:李延广,主治医师,博士 Email:liyanguangsuper@163.com 作者简介:吴宾,硕士生 Email:wubin0917@163.com
更新日期/Last Update: 1900-01-01