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|本期目录/Table of Contents|

冠状动脉经皮介入术治疗高龄非ST段抬高型急性冠脉综合征的疗效

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第4期
页码:
439-441,445
栏目:
临床研究
出版日期:
2018-04-25

文章信息/Info

Title:
Curative effect of percutaneous coronary intervention in patients aged over 80 years with non-ST-segment elevation acute coronary syndrome
作者:
陈 宏 ; 黄 磊; 刁 颖; 王秋林
（成都医学院第一附属医院心内科，四川 成都 610500）
Author(s):
CHEN Hong;  HUANG Lei;  DIAO Ying;  WANG Qiu-lin
(Department of Cardiology, First Affiliated Hospital, Chengdu Medical College, Chengdu 610500, Sichuan, China)
关键词:
非ST段抬高型急性冠脉综合征; 经皮冠状动脉介入治疗; 大于80岁
Keywords:
non-ST-segment elevation acute coronary syndrome;  percutaneous coronary intervention;  over 80 years old
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 评价经皮冠状动脉介入（PCI）治疗在高龄（>80岁）非ST段抬高型急性冠脉综合征(NSTE-ACS)中的安全性和有效性。方法 经冠状动脉造影检查证实冠脉狭窄程度在70%~90%的NSTE-ACS患者175例，根据是否介入治疗分为，介入组84例（发病后3~7 d接受择期PCI），药物组91例（未行PCI术，单纯优化药物治疗）。观察记录两组患者临床特征、1年随访期间主要心血管不良事件。结果 介入组与药物组相比，介入组能显著降低心因住院、血运重建、心绞痛复发风险，在全因死亡、脑梗死、严重的出血事件方面差异无统计学意义。结论 对于高龄NSTE-ACS患者接受PCI术是安全、有效的。
Abstract:
AIM To evaluate the safety and efficacy of percutaneous coronary intervention (PCI) for the treatment of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) in patients over 80 years old. METHODS A total of 175 NSTE-ACS patients with confirmed coronary artery stenosis 70%-90% by coronary angiography were divided into a PCI group and an optimal drug therapy group. Patients in the PCI group underwent PCI 3-7 days after the onset of NSTE-ACS and those in the optimal drug therapy group received only optimal drug treatment. The clinical characteristics of the two groups were observed and major adverse cardiac events during the 1-year follow-up were recorded. RESULTS When compared with those in the optimal drug therapy group, the risk of re-admission for cardiac problems, urgent revascularization, and incidences of recurrent angina in the PCI group were significantly decreased. There were no statistical difference in all-cause mortality, stroke, and major bleeding between the PCI and optimal drug therapy groups. CONCLUSION PCI technique is safe and effective for the treatment of NSTE-ACS in patients over 80 years.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2017-07-31.基金项目：四川省科技厅基金项目资助（2016SZ0052） 通讯作者：王秋林，主任医师，主要从事心血管疾病防治研究 Email：wangredox@163.com 作者简介：陈宏，住院医师，硕士生 Email：349855997@qq.com
更新日期/Last Update: 1900-01-01