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L-精氨酸/一氧化氮通路与血管内皮功能(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1996年第3期
页码:
157-161
栏目:
综述
出版日期:
1996-05-01

文章信息/Info

Title:
-
作者:
刘庆军1　王志华1综述　臧益民2审校
1解放军第91 医院心内科 兖州 272000　2第四军医大学生理学教研室 西安 710032
Author(s):
-
关键词:
精氨酸;  一氧化氮;  血管;  内皮;  动脉粥样硬化;  高血压;  心力衰竭
Keywords:
-
分类号:
-
DOI:
-
文献标识码:
-
摘要:
-
Abstract:
-

参考文献/References

［1］Lowenstein CJ , Snyder SH. Nitric oxide, a novel biologic messenger. Cell 1992; 70 (5) : 705.

［2］ Mitchell JA , HeckerM , Vane JR. The generation of L-arginine in endothelial cells is linked to the release of endothelium-derived relaxing factor. Eur J Pharmacol 1990; 176: 253.

［3］Gold ME, Wood KS, Buga GM , et al. L-arginine causes whereas L-argininosuccinic acid inhibits endothelium-dependent vascular smooth muscle relaxation. Biochem Biophys Res Commun 1989; 161 (2) : 536.

［4］ Hishikawa K, Nakaki T , Tsuda M , et al. Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.Jpn Heart J 1992; 33 (1) : 44.

［5］ Castillo L , Chapman TE, Yu YM , et al. Dietary arginine uptake by the splanchnic region in adult humans. Am J Physiol 1993; 265 (28) : E532.

［6］ Hecher M , Sessa WC, Harris HJ , et al. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: Cultured endothelial cell recycle L-citrulline to L-arginine. PNAS USA 1990; 87:8612.

［7］Sessa WC, Hecker M , Mitchell JA , et al. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-rginine by cultured endothelial cell. PNAS USA 1990; 87: 8607.

［8］ Guoyao WU , Meininger CJ. Regulation of L-arginine synthesis from L-citrulline by L-glutam inein endothelial cell. Am J Physiol 1993;265 (34) : H1965.

［9］Seth P, Kumari R, Dikshit M , et al. Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine. Blood 1994; 84 (8) : 2741.

［10］Tarry WC, Makhoul RJ. L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angio-plasty. Arterioscler Thromb 1994; 14: 938.

［11］Candipan RC, Wang BY, Hsiun PTC, et al.Dietary L-arginine attenuates macrophage infil-tration and intimal hyperplasia after balloon in-jury. JACC 1995; February: 275A.

[12]Cook JP, Singer AH, Tsao P, et al. An-tiatherogenic effects of L-arginine　in the hy-percholesterolemic rabbit. J Clin Invest 1992;90: 1168.

[13]　Radomski MW , Palmer RMJ , Mencada S. AL-arginine/nitric oxide pathway present in hu-man platelets regulates aggregat ion. PNAS USA 1990 ; 87: 5193.

[14]Tsao PS, Theilmeier G, Singer AH, et al. L-arginine attenuates platelet reactivity in 　hypercholesterolemic rabbits.Arterioscler Thromb 1994; 14: 1529.

[15]刘庆军, 吴明媚, 臧益民, 等. N-单甲基左旋精氨酸对犬冠脉内皮依赖性舒张功能及内皮素-1 含量的影响. 第四军医大学学报1994; 15: 261.

[16]Jin JS, D′Alecy LG. Stimulation of endogenousnitric oxide pathway by L-arginine reduces declamp mortality and attenuates hypertension associated with aortic cross-clamp-induced hindlimb ischemia in rats. Hypertension 1995; 26: 406.

[17] Calver A , Collier J , Vallance P. Dilator actions of arginine in human peripheral vasculature. Clin Sci 1991; 81: 695.

[18]Higashi Y, Oshima T , Ozono R, et al. Effect of L-arginine infusion on renal hemodynamics in patient with mild essential hypertension.Hypertension 1995; 25 (Part 2) : 898.

[19]Rubinstein I, Mayhan WG. L-arginine dilates check pouch arterioles in hamsters with heredi-tary cardiomyopathy but not in controls. J Lab Cun Med 1995; 125: 314.

[20]Chandrashekhar Y, M ckenzic Z, Nelson D, et al. L-arginine does not acutely influence en-dothelial function in either resistance or conduct arteries of dogs with pacing induced congestive heart failure. JACC 1995; February:296A.

[21]Salazar FJ , Pinilla JM , Lopes F, et al. Renal effects of prolonged synthesis inhibition of en-dothelium-derived nitric oxide. Hypertension 1992; 20: 113.

[22]Baglis C, Harton P, Engels K. Endo thelial de-rived relaxing factor controls renal hemodynamics in the normal rat kindey. J Am Soc Nephrol 1990; 1: 875.

［23］Rigotti P, Ferraresso M , Morpurg E, et al.Prevention of renal ischemic damage by en-dothelial protecting agents. T ranspla Proc 1995; 27 (1) : 749.

备注/Memo

备注/Memo:
收稿 1995-12-04；修回1996-03-18
更新日期/Last Update: 1996-05-01