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99mTc-MIBI心肌灌注断层显像诊断病毒性心肌炎的初步观察(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1997年第2期
页码:
81-84
栏目:
论著
出版日期:
1997-03-01

文章信息/Info

Title:
The preliminary study of 　99mTc-MIBI SPECT myocardial perfusion image for diagnosing viral myocarditis
作者:
尚玉琨　乔宏庆　侯英萍　刘长滨　陈　敏　张新睿
第四军医大学西京医院核医学科 西安 710033
Author(s):
Shang Yukun; Qiao Hongqing ;  Hou Yingping ; Liu Changbin;  ChenMin;  Zhang Xinrui
Department of Nuclear Medicine, Xijing Hospital, Fourth Military Midical University, Xi′an 710033
关键词:
心肌炎;  病毒性　放射性核素血管造影术
Keywords:
myocarditis;  virus　　radionuclide angiography
分类号:
-
DOI:
-
文献标识码:
-
摘要:
为了探讨Tc-99m-甲氧基异丁基异腈(99mTc-MIBI) 心肌灌注断层显像在病毒性心肌炎诊断中的应用价值, 对130例病毒性心肌炎患者及35例对照组行99mTc-MIBI单光子发射断层(SPECT) 心肌灌注显像, 分析重建后的断层图像, 按是否有花斑样改变和灶性放射性稀疏, 将患者再分为阳性和阴性两组, 分析两组的年龄及性别构成, 计算并比较阳性组、阴性组及对照组的心/肝计数比及心腔/心肌计数比。结果发现: 35例对照组心肌灌注显像正常, 71例患者出现阳性结果, 阳性率为54.6% , 阳性组患者年龄轻、男性多、心/肝比及心腔/心肌计数比明显低于阴性组及对照组。结果提示99mTc-MIBI 心肌灌注断层显像有助于病毒性心肌炎的诊断。
Abstract:
To assess the value of　99mTc-MIBI myocardial perfusion image in the diagnosis of viral myocarditis, 99mTc-MIBI SPECT myocardial perfusion images were performed in 130 patients with viral myocarditis diagnosed on the basis of clinical information and 35 normal persons (controls).The patients were subdivided into two groups according to the results of images. The diffusely inhomogeneous uptake (“patch”) or focal defects were regarded as positive images, and the homogeneous distribution or segmental defects as negative images. The differences between positive and negative groups were compared in age, sex. Cardiac-to-hepatic activity ratio and left ventriculat cavity-to-myocardial count ratio of the patients and the controls were calculated and compared. In 130 patients diagnosed clinically, 71 patients showed positive images. Positive rate was 54.6%. All persons showed normal image in controls. The patients in positive group were younger,more of the male sex. The cardiac-to-hepatic activity ratio and left ventricular cavity-to-myocardial count ratio of the patients in positive group were apparently lower than that of the patients in negative group and the controls. The results suggested that 99mTc-MIBI SPECT myocaridal perfusion image could be helpful to diagnosing viral myocarditis.

参考文献/References

［1］Davies MJ ,Ward DE. How can myocarditis be diagnosed and should it be treated? Br Heart J , 1992; 68: 367.

［2］Peters NS, Poole-Wilson PA. M ocarditis-Continuing clinical and pathologic confusion. Am Heart J , 1991; 121: 942.

［3］ Billingham ME. Acute myocarditis: Is sampling error contraindication for diagnostic biopsy? J Am Coll Cardial, 1989; 14: 921.

［4］ 袁　颖, 林景辉, 潘中允, 等.Tl心肌显像诊断心肌病变价值的初步探讨.中华核医学杂志,1991; 11: 219.

［5］孟玉葆, 刘保平, 孙秉奇, 等150例病毒性心肌炎的心肌断层显像.中华核医学杂志, 1993;13: 109.

［6］ Roberti RR, Van Tosh A , Baruchin MA , et al.Left ventricular cavity-to-myocardial count ratio: A new parameter for detecting resting left ventricular dysfunction directly form tomographic thallium perfusion scintigraphy. J Nucl Med , 1993; 34: 193.

［7］ 周　颖, 屈婉莹, 朱　明, 等.左室腔与心肌计数比值作为左心室功能参数的初步探讨.中华核医学杂志, 1995; 15: 217.

［8］陈国伟, 陈德邵. 病毒性心肌炎.见: 陈国伟,郑宗锷, 主编.现代心脏病学.长沙: 湖南科学技术出版社, 1994: 757～ 767.

备注/Memo

备注/Memo:
Received 1996-11-20；revised 1997-01-17
更新日期/Last Update: 1997-03-01