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结扎兔冠脉4周后左室壁结构与室内压力的改变(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1998年第3期
页码:
148-150
栏目:
论著
出版日期:
1998-05-01

文章信息/Info

Title:
Variation of LV pressure and structure in 4 weeks after ligation of coronary arteries in rabbits
作者:
何振山 齐书英 候云生 李 洁 崔俊玉
石家庄市白求恩国际和平医院心血管内科 050082
Author(s):
He Zhenshan;  Qi Shuying ;  Hou Yunsheng ;  Li Jie;  Cui Junyu
Department of Cardiovascular diseases, The Bethune International Peace Hospital, Shijiazhuang 050082
关键词:
心肌梗死;  急性　心室压　左室重塑　动物模型;  兔
Keywords:
myocardial infarction;  acute 　ventricular pressure 　LV remodeling animal model
分类号:
-
DOI:
-
文献标识码:
-
摘要:
作者研究了结扎后4周兔冠脉左室壁结构及左室腔内不同层面压力变化。结果表明: 急性心梗后4周左室壁出现不均一性增厚, 舒张末容积增加。左室中部收缩期压力由正常时略高于流出道压力转为低于后者, 收缩期压力升高的时间顺序由正常时室中略早于流出道变为迟于后者。这种逆转性变化可能是心梗后左室重塑的重要始动及增重因素。
Abstract:
The variation of structure of LV wall and the pressure of different layers in the LV cavity in 4 weeks after ligation of coronary arteries were studied in rabbits. Our results demonstrated that in 4 weeks after AMI, the LV wall became hypertrophic and end diastolic volume was enlarged; the systolic pressure at mid layer of the LV fell down to a level lower than in the outflow; but its normal level was higher than the later and the systolic pressure rising time of the mid layer of the LV became later than in the outflow; but in the normal condition it was earlier than the later. These reverse changes are probably the important initiate and accelerate factors to LV remodeling.

参考文献/References

［1］何振山, 宁佩萸.急性心梗后左室重构.医学综述, 1994; 3: 1.

［2］Sharpe N. Ventricular remodeling following myocardial infarction. Am J Cardiol, 1992; 70 (9) : 20c.

［3］何振山, 宁佩萸, 于富军, 等.急性心肌梗塞4周的左室重构.解放军医学杂志, 1996; 21 (6) : 4290.

［4］Davidoff R. Spetial and temporal variability in the pattern of recovery of ventricular geometry and function after acute occlusion and reperfusiion. Am Heart J , 1994; 127: 1231.

［5］何振山, 卫亚利, 于富军, 等. 冠心病左室形态与功能多变量分析.数理医药学杂志, 1997; 10 (1) : 22.

备注/Memo

备注/Memo:
(收稿1997-11-03)
更新日期/Last Update: 1998-05-01