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|本期目录/Table of Contents|

心脏AT1受体及其信号通路(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1999年第4期
页码:
257-259
栏目:
综述
出版日期:
1999-07-01

文章信息/Info

Title:
-
作者:
王尔松1　匡雄辉2 综述
1上海医科大学儿科医院儿研所　2上海市沪东医院内科, 上海 2000129
Author(s):
-
关键词:
心脏　受体;  血管紧张素; AT1　血管紧张素Ⅱ
Keywords:
-
分类号:
-
DOI:
-
文献标识码:
-
摘要:
-
Abstract:
-

参考文献/References

［1］Lee YA ,Lindpainter K. The cardiac renin-angiotensin system from basic research to clinical relevance. Arzneimittelforschung , 1993; 43(2A) : 201.

［2］Bumpus FM,Catt KJ, Chiu AT,et al.Nomenclature for angiotensin receptors.A report of the nomenclature committee of the council for high blood pressure research.Hypertension, 1991; 17:720.

［3］Dostal DE, Hunt RA , Kule CE, et al. Molecular mechanisms of angiotensin Ⅱ in modulating cardiac function: intracardiac effects and signal transduction pathways. J Mol Cell Cardiol, 1997; 29 (11) :2893.

［4］Sadoshima J , Izumo S. Molecular characterization of angiotensin Ⅱinduced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: critical role of the AT1 receptor subtype. Circ Res,1993; 73 (3) : 413.

［5］Bergsma DJ , Ellis C, Kumar C, et al. Cloning and characterization of a human angiotensin Ⅱtype1 receptor. Biochem Biophys Res Commun, 1992; 183 (3) : 989.

［6］Iwai N , Inagami T. Identification of two subtype in the rat type1 angiotensin Ⅱ receptor. FEBS Lett, 1992; 298: 257.

［7］Sandberg K. Structural analysis and regulation of angiotensin Ⅱ receptors. Trends Endocrinol etab, 1994; 5: 28.

［8］Conchon S,Barrault MB,Miserey S, et al. The C-terminal third intracellular loop of the ratA T1a angiotensin receptor plays a key role in G protein coupling specificity and transduction of the mitogenic signal. J Biol Chem , 1997; 272 (41) : 25566.

［9］Wang C, Jayadew S, Escobedo JA. Identification of a domain in the angiotensin Ⅱ type1 receptor determining Gq coupling by the use of receptor chimerase. J Biol Chem , 1995; 270 (28) : 16677.

［10］Griendling KK, Lassegue B,Alexander RW. Angiotensin receptors and their therapeutic implications. Annu Rev Pharmacol Tox icol,1996; 36: 281.

［11］Hunyady L , Bor M , Balla T, et al. Identification of a cytoplasmic Ser-Thr-Leu motif that determines agonist-induced internalization of the AT1 angiotensin receptor. J Biol Chem , 1994; 269 ( 50) :31378.

［12］Thomas WG, Baker KM ,Motel TJ , et al. Angiotensin Ⅱ receptor endocytosis involves two distinct regions of the cytoplasmic tail. J biol Chem , 1995; 270 (38) : 22153.

［13］ Su B,Martin MM , Beason B, et al. The genomic organization and functional analysis of the promoter for the human angiotensin Ⅱtype1 receptor. Biochem Biophys Res Commun, 1994; 204 (3) : 1039.

［14］Guo DF, Furuta H,Mizukoshi M , et al. The genomic orgnization of human angiotensinê type-1 receptor. Biochem Biophys Res Commun, 1994; 200 (1) : 313.

［15］Gallagher AM ,Bahnson TD, Yu H, et al. Species variability in angiotensin receptor expression by cultured cardiac fibroblasts and the infarcted heart. Am J Physiol, 1998; 274 (3pt2) : H801.

［16］ Dostal DF,Booz GW ,Baker KM. Angiotensin Ⅱ signaling pathways in cardiac fibroblasts: conventional versus novel mechanisms in mediating cardiac growth and function. Mol Cell Biochem , 1996; 157:15.

［17］Hein L , Stevens ME,Barsh GS, et al. Overexp ression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block.Proc Natl Acad Sci USA , 1997; 94 (12) : 6391.

备注/Memo

备注/Memo:
(收稿1998-08-13　修回1999-06-28)
更新日期/Last Update: 1999-07-01