我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

超声检测大鼠心脏结构与功能(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第2期
页码:
87-89
栏目:
论著
出版日期:
2000-03-25

文章信息/Info

Title:
Detection of cardiac structure and function in rats by echocardiography
作者:
商慧华1;  钱蕴秋1;  暴军香2;  周晓东1;  朱永胜1;  张立藩2
第四军医大学 1西京医院超声科; 2 空军医学系， 陕西 西安 710032
Author(s):
SHANG Hui-hua1; QIAN Yun-qiu1; BAO Jun-xiang2; ZHOU Xiao-dong1; ZHU Yong-sheng1; ZHANG Li-fan2
1Department of Ultrasonography,Xijing Hospital;2 Faculty of Aeroforce Aviation Medicine,Fourth Military Medical University,Xi’an 710032，Shaanxi,China
关键词:
超声心动描记术; 多普勒; 心脏; 大鼠
Keywords:
echocardiography;  Doppler; heart; rats
分类号:
R445.1
DOI:
-
文献标识码:
A
摘要:
应用二维与多普勒超声心动图观察大鼠心脏结构和功能，并将左室重量的超声测值与实际测值相比较，以评价该检测方法的可行性、准确性。将15只正常SD大鼠麻醉后，应用经胸7.5 MHz超声检测左室结构指标和左室重量，然后处死大鼠测左室重量。结果显示超声测定的大鼠左室重量与尸解结果高度相关(r=0.9314,SEE=0.0376,P＜0.0001)。证实经胸超声心动图可以清晰显示大鼠心脏结构与多普勒血流信息，是一种准确评价大鼠心脏结构和功能的无创方法。
Abstract:
This study was to evaluate the cardiac structure and function by echocardiography in rats,and to assess its feasibility and accuracy by comparing the LV mass of normal rats detected by 2DE with postmortem. Fifteen normal rats weighting 200 g～300 g were anesthetized. all indices of LV contractile function and LV mass was studied by echocardiography and then, the heart was to dissected weigh the left ventricle in the scales. The results of heart structure,mitral valve,aortic and pulmonary artery flow could be revealed clearly by echocardiography. The LV mass of normal rats correlated well with postmortem (r=0.9314,SEE=0.0376,P＜0.0001). It’s proved that the transthoracic echocardiography can be used to accurately and noninvasively assess cardiac structure and function of the rats.

参考文献/References

［1］Devereux RB,Reichek N. Echocardiographic determination of left ventricular mass in man:Anatomic validation of the method［J］. Circulation,1977,55(4):613.

［2］Sahn DJ,Demaria A,Kisslo J,et al. Recommendations regarding quantitation in M-mode echocardiography:results of a survey of echocardiographic measurements［J］.　Circulation,1978,58:1072.

［3］Litwin SE,Katz SE,Morgan JP,et al. Serial echocardiographic assessment of left ventricular geometry and function after large myocardial infarction in the Rats［J］. Circulation,1994,89:345.

［4］Pawlush DG,Moore RL,Musch TI,et al. Echocardiographic evaluation of size,function,and mass of normal and hypertrophied rat ventricle［J］. J Appl Physiol,1993,74:2598.

［5］Poulos JE,Gower WR,Subllebarger JT,et al. Congestive heart failure:increased cardiac and extracardiac natriuretic peptide gene expression［J］. Cardiovasc Res,1996,32:909.

备注/Memo

备注/Memo:
收稿日期：1999-02-25.
更新日期/Last Update: 2000-03-25