含服普萘洛尔治疗高血压病的血流动力学观测(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2000年第2期
- 页码:
- 110-112
- 栏目:
- 论著
- 出版日期:
- 2000-03-25
文章信息/Info
- Title:
- Effect of sucking propranolol on hemodynamic of patients with hypertension
- Author(s):
- WANG Qin-xian; YU Zi-dong; XU Wei-bao; LIANG Hong-mei; YUAN Zheng-bo; PAN Yue-min
- Department of Cardiology, People′s Hospital of Xinchang, Xinchang 312500,Zhejiang, China
- Keywords:
- hypertension; propranolol; hemodynamic
- 分类号:
- R544.1
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 观察普萘洛尔治疗高血压的血流动力学变化,并与硝苯啶疗效比较. 方法 采用血流动力学信息检测仪(CD-Ⅳ),检测高血压病患者舌下含服普萘洛尔和硝苯啶前后的血流动力学参数。结果 舌下含服普萘洛尔能较迅速地降压,降低心肌耗氧量,提高射血分数和心肌缺血阈值,其在降低心肌耗氧量和改善心肌缺血阈值上优于硝苯啶。结论 本检测方法对指导临床用药有重要的实用价值;舌下含服普萘洛尔疗效优于硝苯啶。
- Abstract:
- Aim To observe the change of hemodynamics when propranolol is used to treat hypertension and compare with the effects of nifedipine.Methods Adopt the detective apparatus of hemodynamic information (CD-Ⅵ) and examine the parameters of hemodynamics before and after the persons suffering from hypertension take propranolol and nifedipine.Results Taking propranolol can quickly reduce blood pressure and myocardium consume volume oxygen,raise ejection fraction and myocardium ischemic threchold. It is prior to nifedipine in reducing myocardium consume volume oxygen and improving myocardium ischemic threshold.Conclusion This way of examination has important values to direct clinical using of medicine,Taking propranolol has better effects than nifedipine.
参考文献/References
［1］陈维洲. β肾上腺素受体阻滞剂［A］. 见:陈 修,陈维洲,曾贵云. 新血管药理学［M］. 北京:人民卫生出版社,1997:172,181.
［2］Halabi A. Hemodynamic effects of brefanolol and propranolol assessed noninvasive methods in patients with arterial hypertension［J］. Cardiovasc Pharmacol, 1990,16(1):81.
［3］饶曼人. 抗心肌缺血药进展［A］. 见:翁心植,吕俊升,戚文航. 心肺血管疾病研究进展［M］. 北京:北京医科大学,中国协和医科大学联合出版社,1994:167.
备注/Memo
- 备注/Memo:
- 收稿日期：1999-06-02.
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更新日期/Last Update: 2000-03-25