我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

D-二聚体定量检测对判定不稳定性心绞痛血栓成分的临床意义(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第4期
页码:
267-269
栏目:
论著
出版日期:
2000-08-01

文章信息/Info

Title:
The clinical significance of test D-dimer in judging the composition of unstable angina coronary thrombi
作者:
孟涛1;  张晋兰1;  周春兰2;  马文英1;  蔡芙莉1;  贾莉慧1;  胡凯2;  王健2;  闫峻1
西安市中心医院: 1. 心内科, 2. 血液病研究所, 陕西西安710003
Author(s):
MENG Tao;  ZHANG Jin-lan;  ZHOU Chun-lan;  MA Wen-ying;  CAI Fu-li;  JIA Li-hui;  HU Kai;  WANG Jian;  YAN Jun
Department of cardiology, Xi'an Central Hospital,Xi'an 710003, Shaanxi, China
关键词:
D-二聚体;  心绞痛;  不稳定性;  心肌梗死;  急性;  血栓
Keywords:
D-dimer;  angina;  unstable;  myocardial infarction;  acute;  thrombi
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨 D-二聚体检测在判定不稳定性心绞痛 (UAP)血栓成分的价值及临床意义。方法 选择住院按亚型诊断、分组的 UAP患者 5 6例 ,急性心肌梗死 (AMI)患者 16例 ,稳定性心绞痛 (SAP)患者 2 3例 ,采用胶体金方法动态检测患者静脉血中的 D-二聚体含量。结果 UAP亚组中 D-二聚体含量 初发型 0 .73± 0 .31mg/ L ;恶化型 1.0 8± 0 .36 mg/ L ;混合型 0 .49± 0 .10 mg/ L ;梗死后 0 .76± 0 .2 1mg/ L ;AMI组 1.83± 0 .6 4m g/ L。与 SAP组 D-二聚体含量 0 .38± 0 .16 m g/ L比较 ,均存在显著差异 (P<0 .0 5 )。恶化组、AMI组与 SAP组比较 ,差异最为显著 (P<0 .0 1)。结论 D-二聚体定量检测是判定 U AP血栓形成、血栓成分相对特异的敏感指标。
Abstract:
Aim To study the value and clinical significance of D dimer in judging the composition coronary artery thrombi of unstable angina(UAP) patients. Methods Fifty six hospitalized patients group diagnosed and categorized as UAP,16 paitents as acute myocardial infarction (AMI), 23 patients as stable angina pectoris(SAP). The D dimer in their venous blood were ested dymatically by ELISA methods. Results D dimer in UAP group:new angina 0.73±0.31 mg/L; accelerated angina 1.08±0.36 mg/L;mixed angina 0.49±0.10 mg/L; post infarction unstable angina 0.76±0. 21 mg/L; AMI group 1.83±0. 64 mg/L. The content of D-dimer in SAP 0.38±0.16 mg/L. The difference is significant (P<0. 05). The accelerated angina group and AMI group compared with SAP group seperately, the difference ismore sigificant (P<0. 01). Conclusion Test the content of D-dimer is a comparative distinctive sensitive marker in the judgement of coronary thrombosis and its composition.

参考文献/References

[1] 陈纪林, 徐义枢, 陈在嘉. 不稳定性心绞痛溶栓治疗现状的评述[J]. 中华心血管病杂志, 1997, 25 (6) : 409.

[ 2 ] 包承鑫. D2二聚体测定的生理基础和临床意义[J ]. 血栓与止血杂志, 1995, 2 (3) : 122.

[3] 胡大一, 项志敏. 不稳定性心绞痛溶栓治疗的评价[J ]. 中华心血管病杂志, 1996, 24 (3) : 165.

[4] 迟东升, 吾柏铭. D2二聚体在心血管疾病中的应用价值[J ]. 心血管病学进展, 1998, 19 (1) : 18.

[5] TIMI III investigators. Effects of tissue plasm inogen activators and a comparison of early invasive and conservative strategy in unstable angina and non-Q wave myocardial infarction: Results of the TIMI III trial[J]. Circulation, 1994, 89 (8) : 1545.

[6] 张家祥. D-二聚体检测的临床应用[J ]. 血栓与止血杂志, 1995,

2 (3) : 142.

[7] Lee AJ, Fowkes GR, Lowe GD, et al. Determ inants of fibrin D-dimer in the Edinburgh Artery Study [J]. Arteriosder Thromb Vasc Biol, 1995, 15 (2) : 1094.

[8] Salmaa V, Stinson V, Kark JD, et al. Association of fibrionlytic parameters with early atheroslcerosis [A ]. The ARIC Study. Atheosclerosis risk in communities study [C]. Circu lation,1995, 91 (4) : 284.

备注/Memo

备注/Memo:
收稿日期：1999-08-30.
更新日期/Last Update: 2000-08-01