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|本期目录/Table of Contents|

抗心律失常药物和离子通道(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第2期
页码:
143-145
栏目:
综述
出版日期:
2001-03-01

文章信息/Info

Title:
-
作者:
徐有秋
上海第二医科大学生理学教研室，上海2OOO25
Author(s):
-
关键词:
药物; 抗心律失常; 离子通道
Keywords:
-
分类号:
R972；R541.7
DOI:
-
文献标识码:
C
摘要:
-
Abstract:
-

参考文献/References

[1]Echt DS，Liebson PR，Mitchell LB，et al．Mortality and morrbidity in patients receiving encainide,flecainide or placebo.The cardiac arrhythmia suppressioon trial[J]．N Engl J Med．1991，324:781-787.

[2]Th Cardiac Arrthythmio Suppression Trial II investigators．Effact of the antiarrhythmic agent moricizine on survival after myocardial infarction[J].N Engl J Med．1992，327:227-233．

[3]Waldo AL，Carom AJ，DeRuyter H，et al.Effect of d-sotelol on mortality in patients with left ventricular dysfuction after recent and remote myocardial infarction[J].Lancet，1996,348:7-12．

[4]Guerra PC, Talajic M,Roy D,et al.Is there a future for antiarrhythmic durg therapy?[J]．Drugs.1998．56:767-781.

[5]Nattel S,Experimental evidence for proarrhythmic mechanisms of antiarrhythmic drugs[J]．Cardiovasc Res，1998,37:567-577.

[6]Wijffels MCEF,Kirchhof CJHJ，Dorland R，et al. Atrial fibril1ation begets atrial fibfillation:A study in awake chronically instrumented goats[J]. Circulation，1995,92:1965-1968．

[7]Xu YQ,Pickoff AS,Clarkson CW．Developmental changes in the effects of lidocaine on sodium channels in rat cardiac myocytes[J]．J Pharmacol Exp Ther,1992,262:670-676．

[8]Swynghedauw B．Molecular mechanisms of myocardial remodeling[J]．Physiol Rev,1999,79:215-268．

[9] Hondeghem LM．Ideal antiarrhymic agents:Chemical defribrillators[J]．J Cardiovasc Electrophysol,1991,2:S169-S177．

[10] Shaw RM,Rudy Y．The vulnarable window for unidirectional block in cardiac tissue: Characterization and dependence on membrane excitability and intercellular coupling [J].J Cardiovasx Electrophysiol,l995,6:115-131.

[11]Carlsson L,Abrahamsson C,Andersson B,et al.Proarrhythmic effects of the class III agent almoskalant:Importance of infusion rate,QT dispersion,and early afterdepolarizations[J]．Cardiovasc Res,1993，27:2186-2193．

[12]Carmeliet E．Use-dependent block sad use-dependent unblock of the delayed rectifier K+ current by almokalant in rabbit ventricular myocytes[J]．Circ Res,1993，73:857-868.

[13]Camm AI，Yap YG．What should we expect from the next generation of antiarrhythmic durgs?[J]．J Cardiovasc Electrophysiol，1999,10:307-317．

[14] Nattel S．The molecular and ionic specificity of antiarrhythmic drug actions[J].J Cardiovasc Electrophysiol，1999，10:272-282．

[15] Carmeliet E．Antiarrhythmic drugs and ion chennels,Have we made the connection?[J]．J Cardiovasc Electrophysiol，1999，19:755-59．

备注/Memo

备注/Memo:
收稿日期：2000-03-20.
更新日期/Last Update: 2001-03-01