我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

左旋精氨酸对犬实验性冬眠心肌的保护作用(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第5期
页码:
360-362
栏目:
论著
出版日期:
2001-09-01

文章信息/Info

Title:
Protective effect of L-arginine on hibernating myocardium in dog-model
作者:
张　华;  贾国良
第四军医大学西京医院心内科, 陕西西安710032
Author(s):
ZHANG Hua;  JIA Guo-liang
Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an Shaanxi,710032, China
关键词:
冬眠心肌;  左旋精氨酸
Keywords:
hibernating myocardium;  L-arginine
分类号:
Q517　
DOI:
-
文献标识码:
A
摘要:
目的 观察左旋精氨酸对冬眠心肌功能、代谢与结构的影响。方法 30 只犬短期冬眠心肌模型随机分为3 组:A 组(n= 14) 灌注生理盐水;B 组(n= 8) 灌注左旋精氨酸; C 组(n= 8) 灌注L-MNNA。结果 3 组间左心室舒张末期 压、血乳酸、ATP 含量及电镜下结构改变差异显著。左旋精氨酸组明显优于其他两组。结论 左旋精氨酸可改善冬 眠心肌、代谢与功能结构。
Abstract:
AIM To investigate L-arginine (L-arg) influcence on function,metabolic and structure of myocardium. METHODS The thirty dogs which dog-models under short-hibernating myocardium was established were randomly divided into three groups. A (control) group (n= 14)perfusing 9 g/L NaCl, B group (n = 8) perfusing l-arg, C group (n = 8) perfusing L-MNNA.RESULTS LVEDP, L actate release, ATP content and ultrastructure have remarkable difference among three groups. L-arg group out standingly was superior to other groups. CONCLUSION L-arg can improve the function,metabolic and structure of hibernating myocardium.

参考文献/References

[1] Nagueh SF, Mikati I, Weilbaecher D, et al. Relation of the contractile reserve of hibernating myocardium to myocardials structure in humans[J]. Circulation, 1999, 100 (5) : 490.

[2] Chen C, Liu J , Hua D, et al. Impact of delayed reperfusion of myocardal hibernation on myocardial ultrastructure and function and their recoveries after reperfusion in pig model of myocardial hibernation[J]. Cardiovasc Pathol, 2000, 9 (2) : 67.

[3] Keller AM , Connon PJ. Effect of graded reductions of coronary pressure and flow on myocardial metabolism and performance: a model of “hibernating”myocardial[J]. J Am Coll Cardiol,1991, 17(7) : 1661- 1667.

[4] Marshall RC, Tillisth JH, Phelps ME, et al. Identification and differentiation of resting myocardial ischemia and infarction in man with postron computed tomography: 18F labeled flurooxyglocuse and N-13-ammonia[J]. Circulation, 1993, 67: 766-778.

[5] Ignarro LJ. Nitric oxide: a novel signal transduction mechanism for transcellual communication [J]. Hypertension, 1990, 16: 477- 483.

备注/Memo

备注/Memo:
收稿日期：2000-06-02.
更新日期/Last Update: 2001-09-01