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|本期目录/Table of Contents|

一氧化氮在心肌细胞凋亡中的作用(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第1期
页码:
61-63
栏目:
综述
出版日期:
2003-01-01

文章信息/Info

Title:
Effect of nitric oxide on myocardial apoptosis
作者:
张博; 裴建明; 高峰
第四军医大学生理学教研室,陕西 西安 710032
Author(s):
ZHANG Bo;  PEI Jian-ming;  GAO Fen
Department of Physiology, Fourth Military Ledical University, Xi'an, Xhaanxi 710032, China
关键词:
一氧化氮; 心肌细胞; 凋亡
Keywords:
nitric oxide;  cardiacmyocytes;  appoptpsise
分类号:
Q255;R363.13
DOI:
-
文献标识码:
A
摘要:
作者综述了一氧化氮(NO)对心肌细胞凋亡的作用机制。NO对心肌细胞的作用有双重性:既是组织损伤的中间介质,又在心肌缺血/再灌注损伤中有保护心肌作用。它可通过氧化应激反应,作用于心肌细胞的一些蛋白质、酶类、细胞因子以及胞液的钙超载等途径来影响心肌细胞凋亡。
Abstract:
Nitric oxide (NO) has adouble effect on cardiacmyocytes: It is not only the medium of tissue damage, but play a protective role in myocardial ischemia/reperfusion as well. NO may influence myocardial apoptosos via oxidizing stress, affecting on protein or enzyme, cytokinecy, and cytoplasmic calcium over loading.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2001-09-08.
更新日期/Last Update: 2003-01-01