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|本期目录/Table of Contents|

冠状动脉内支架术预后的性别差异(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第1期
页码:
47-49
栏目:
临床研究
出版日期:
2004-01-01

文章信息/Info

Title:
Sex differences in outcomes of elective coronary stenting in patients with coronary artery disease
作者:
蒋利; 沈卫峰; 张建盛; 张瑞岩; 吕安康; 胡健
上海第二医科大学附属瑞金医院心脏科,上海 200025
Author(s):
JIANG Li;  SHEN Wei-feng;  ZHANG Jian-sheng;  ZHANG Rui-yan;  LU An-kang;  HU Jian
Department of Cardiology, Ruijin Hospital, Shanghai Second Medial University, Shangai 200025,China
关键词:
冠状动脉疾病; 支架; 性别; 预后
Keywords:
coronary diseade;  stent;  sex;  prognosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:探讨性别因素对冠心病患者选择性冠状动脉(冠脉)内支架术近期结果和远期预后的影响。方法:连续682例冠心病患者行选择性冠脉内支架术,其中男性 543例,女性139例。比较二者支架术近期结果及远期随访。结果:男、女两组支架术成功率(95.8%和97.1%,P=0.464)相似,但女性手术并发症较男性显著增多(5.0%和0.9%,P=0.003)。多因素分析显示性别是手术并发症的独立预测因素(RR4.86,95%CI1.29～18.4,P=0.020)。随访16±8月,随访率为94.8%。随访期内,男、女两组心脏事件发生率(21.4%和22.3%)、病死率(4.6%和 4.6%)及造影再狭窄率(13.1%和 14.6%)差异均无显著性 (均 P>0.05),多因素分析显示,性别不是冠脉内支架术后远期心脏事件和死亡的独立预测因素。结论:性别对选择性冠脉内支架术远期预后无明显影响,但女性患者手术并发症率高。
Abstract:
AIM:To investigate the effect of sex on initial and long-term outcomes following coronary stenting in patients with coronary artery disease. METHODS: This prospective study comprised 682, consecutive patients with coronary artery disease who underwent selective coronary stenting, including 139 women(female group) and 543 men(male group), the initial results and long-term follow-up outcomes were compared. REULTS: There was no significant difference in the procedural success rate between the two groups (97.1% vs 95.8%)(P=0.464), but the proedural complication rate was higher in the female group than in the male group(5.0% vs 0.9%,P=0.003). Multivariate analysis showed that sex was an independent predictor of procedural complications (relative risk 4.86,95% CI 1.29～18.4, P=0.020). The follow-up rate was 94.8% (mean duration, 16±8 months). There were no significant differences in the occrrence rates of composite events (22.3% vs 21.4%), mortality (4.6% vs 4.6%) and angiographic restenosis (14.6% vs 13.1%) between the tow groups (all P>0.05). Logistic regression analysis also indicated that sex was not an independent predicator for long-term composite events and mortality. CONCLUSION: Sex may have no influence on long-term outcomes of elective coronary stenting, but it may be an independent predictor of procedural complications.

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备注/Memo

备注/Memo:
收稿日期：2002-12-15
更新日期/Last Update: 2004-01-01