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同种异体带瓣主动脉行主动脉根部置换的临床效果(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第3期
页码:
242-243,246
栏目:
临床研究
出版日期:
2004-05-01

文章信息/Info

Title:
Clinical results of homologuous aortic with valve replacement of aortic root
作者:
池一凡1; 孙忠东1; 侯文明1; 杨铁南1; 牛兆掉1; Th. Caus2;  Th. Mesana2
1. 青岛大学医学院附属育岛市立医院心外科，山东青岛266011; 2.法国马塞Timone医院成人心脏外科中心，法国 马塞 13385
Author(s):
CHI Yi-fan; SUN Zhong-dong; HOU Wen-ming; YANG Tie-nan; NIU Zhao-zhuo; Caus T; Mesana T
1.Department of Cardiovascular Surgery,Qingdao Municipal Hospital，Medical College of Qingdao University, Qingdao，Shandong 266011，China; 2.The Center of Mature Heart Surgery of Timone Hospital，Marseille 13385,France
关键词:
主动脉瓣膜病; 主动脉根部重建; 同种异体带瓣主动脉
Keywords:
aorticv alved isease; aortic root reconstruction; homologuous aortic with valve
分类号:
R654.3
DOI:
-
文献标识码:
A
摘要:
目的:探讨应用低温保存的同种异体带瓣主动脉行主动脉根部重建手术的临床效果.方法:85例主动脉瓣膜病变患者行同种主动脉根部置换手术，术后随访观察临床结果。结果:随访39±13(1.5-91)个月。早期手术死亡率1%(1/85),远期手术死亡率6%(5/85)，与术前比较心功能明显改善(P<0.05);术后随访心内膜炎发生率占2%(2/85);生存者中瓣膜无或有轻度返流84%(66/79)，中度返流16% (13/79).结论:同种异体带瓣主动脉根部重建手术效果可靠，且并发症少。
Abstract:
AIM:To evaluate the clinical results of homologuous aortic with valve replacement for aortic root diseases. METHODS:There were 85 patients underwent aortic root replacement with a cryopreserved homologuous aortic with valve. The incidence rate of complications were carried out. RESULTS:The mean follow-up time was 39±13 (range 1.5-91) months. Early and late mortality postoperatively was 1%(1/85) and 6%(5/85)，respectively. The morbidity endocarditis was only 2% (2 /85).The heart function have markly improvement postoperatively. Homograft valve function showed no or trivial and moderate aortic regurgitation in survival patients was 84% (66/79) and 16%(13/79), respectively. CONCLUSION: The aortic root replacement with cryopreserved hornologuous aortic with valve has acceptable hospital mortality and excellent mid-term results compare with other artificial valve.

参考文献/References

[1] Yankah AC, Klose H, Musci M,et al. Geometric mismatch beween homograft (alograft) and native aortic root: a 14-year clinical experience[J]. Eur J Cardiothorac Surg,2001,20(4):835-841.

[2] O'Brien MF, Harrocks S, Stafford EG,et al. The homograft aortic valve,a 29-year, 99.3% follow up of 1,022 valve replacements[J].J Heart Valve Dis,2001,10(2),334-344.

[3] Matsuki O, Robles A, Gibbs S, et al. Long-term performance of 555 aortich omografts in the aortic position[J].Ann Thorac Surgery,1988,46(1):187-191.

[4] Riberi A, Caus T, Mesana T, et al. Aortic valve or root replacement with cryopreserved homograft for active infectious end ocarditis[J].Cardiovascular Surgery,1997,5(2):579-583.

[5]Yankah A C,Klose H,Petzina R,et al.Surgical management of acute aortic root endocarditis with viable homograft,13-year experience[J].Eur J Cardiothorac Surg,2002,219(2):260-267.

[6] Koolbergen DR, Hazekamp MG,de Heer E,et al.The pathology of fresh and cryopreserved homograft heart valves, an analysis of forty explanted homograft valves[J].J ThoracC ardiovasc Surg,2002,124(4),689-697.

备注/Memo

备注/Memo:
收稿日期：2003-6-20
更新日期/Last Update: 2004-05-01