我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

心脏毒覃碱样乙酞胆碱受体研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第4期
页码:
371-374
栏目:
综述
出版日期:
2004-07-01

文章信息/Info

Title:
-
作者:
曾菊绒1; 藏伟进1; 康新勤1; 藏益民2
1.西安交通大学药理学教研室，陕西西安710061;2.第四军医大学生理学教研室
Author(s):
-
关键词:
M 受体; 心脏; 分布; 密度变化
Keywords:
-
分类号:
R544; R96
DOI:
-
文献标识码:
A
摘要:
本文将近几年心脏毒草碱样乙酷胆碱(ACh)受体(MAChRs，简称m受体)在分型、结构、信号转导及疾病时的变化等作一综述。
Abstract:
-

参考文献/References

[1] Ponicke K, Heinroth-Hoffmann I, Brodde OE. Demonstration of functional M3-muscarinic receptor inventricular cardiomyocytes of adult rats[J].Br J Pharmacol,2003,138(1):156一160 .

[2] Krejci A, Tucek S. Quantitation of mRNAs for M (1) to M(5) subtypes of muscarinic receptors in rat heart and brain cortex [J] . Mol Pharmacol,2002,61(6):1267一1272.

[3]Zolk O ,Kouchi I, Schnabel P ,et al .Heterotrimetric G proteins in heart disease[J].Can J Physiol Pharmaco1,2000,78:187一198 .

[4] Stefan D, Chris J, Van K, et al. Muscarinic receptor in mammalian heart[J].Pharmacol Res,2001,44,161一182.

[5] Lo SH, Liu LM, Huang LW, et al. Decrease of muscarinic M2 cholinerceptor gene expression in the heart of aged rat[J].Neurosci Lett, 2001,300,185一187.

[6] Kurogouchi, Fumio,Nakane, et al. Heterogeneous distribution of [ beta ]-adreneoceptors and muscarinic receptors in the sinoatrial node and right atrium of the dog[J].Clin Exp Pharmacol Physiol ,2002,29(8):666一672.

[7] Oberhauser V, Schwertfeger E, Rutz T, et al. Acetylcholine release in human heart atrium,influence of muscarinic auto receptors, diabetes and age[ J].Circulation,2001,103:1638一1643.

[8]Dunlap ME,BibevskiS ,Rosenberry TL,et al .Mechannism of altered vagal control in heart failure,in fluence of muscarinic recepter s and acetylcholinesterase activity[ J] .Am J Physiol Heart Circ Physiol,2003, 285( 4):H 1632一H1640.

[9] Neglia D, Sambuceti G, Iozzo P, et al. Myocardial metabolic and receptor imaging in idiopathicdilated cardiomyopath[ J] . Eur J Nucl Med Mol Imaging,2002,29(10): 1403一1413.

[10]Li Y, Anand S, Madhu B. Inactivation of enhanced expression of Gi proteins by pertusis toxin attenuates the development of high blood pressure in spontaneously hypertensive rats[J].Circ Res, 2002,91,247一254.

[11]杨诏旭，蔡振杰，王跃民，等.乙醉胆碱诱发犬急性心房抓动模型的研究 [ J].心脏杂志，2002,14(3):195一198.

[12]Dobrev D, Graf E, Wettwer E, et al. Molecular basis of down regulation of G-Protein-Coupled inward erctifyin K+-current (IK -A ch )in chronic human atrialf ibrillation decreasei n GIRK4- mRNA correlates with reduced IK-Aa and muscarinic receptor mediated shortening of action potential[J].Circulation,2001，104( 21 ):2551一2557.

[13]Okumara S, Kawabe J, Yatani A, et al. Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium mediated cardiac regulation[J].Circulation,2003 , 93: 364一371.

[14] Marie C, Wellner K, Kirsten B, et al. Overexpressed Al adenosine receptors reduce activation of acetylcholine-sensitive K+ current by native muscarinic M2 receptors in rat atrial myocytes[ J].Circ Res,2000,86:643一648.

[15]Garofolo MC, Seidler FJ, Auman JT, et al. Beta-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart[J ].Am J Physiol Regul Integr Comp Physiol,2002,282(5):1356一1363.

[16]Myslivecek J, Trojan S. Regulation of adrenoceptors and muscarinic recepters in the heart[ J].Gen Physiol Biophys,2003,22 (1 ) :3一14.

备注/Memo

备注/Memo:
收稿日期：2003-4-18
更新日期/Last Update: 2004-07-01