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|本期目录/Table of Contents|

利用心电图鉴别长QT综合征基因类型的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第5期
页码:
484-486
栏目:
综述
出版日期:
2005-10-05

文章信息/Info

Title:
-
作者:
赵永辉 崔长琮
西安交通大学第一医院心血管内科, 陕西 西安 710061
Author(s):
-
关键词:
心律失常 心电描记术 基因 长QT综合征 分子遗传学
Keywords:
-
分类号:
R540.41
DOI:
-
文献标识码:
A
摘要:
长QT综合征(LQTS)的分子遗传学取得突破性进展,基因型表现型相关性研究表明LQTS患者的临床表现均是基因特异的。本文综述了利用静息心电图、运动负荷心电图及动态心电图鉴别LQTS基因类型的研究进展,此方法有助于进一步寻找致病基因和突变位点以及基因特异性治疗的开展。
Abstract:
-

参考文献/References

[1]Allan WC.The long QT syndrome [J]. N Eng J Med, 2000,17:514-515.

[2] Chiang CE, Roden DM. The long QT syndromes: genetic basis and clinical implications[J]. J Am Coll Cardiol, 2000,36:1-12.

[3] Wilde AA, Roden DM. Predicting the longQT genotype from clinical data: from sense to science[J]. Circulation,2000,102:2796-2798.

[4] Schwartz PJ, Priori SG, Spazzolini C, et al. Genotypephenotype correlation in the longQT syndrome: genespecific triggers for lifethreatening arrhythmias[J]. Circulation, 2001,103:89-95.

[5] Zhang L, Timothy KW, Vincent GM, et al. Spectrum of STTwave patterns and repolarization parameters in congenital longQT syndrome: ECG findings identify genotypes[J]. Circulation, 2000,102:2849-2855.

[6] Takenaka K, Ai T, Shimizu W, et al. Exercise stress test amplifies genotypephenotype correlation in the LQT1 and LQT2 forms of the longQT syndrome[J]. Circulation,2003,107:838-844.

[7] Viitasalo M, Oikarinen L, Vaananen H, et al. Differentiation between LQT1 and LQT2 patients and unaffected subjects using 24hour electrocardiographic recordings[J]. Am J Cardiol, 2002,89:679-685.

[8] Shimizu W, Antzelevitch C. Cellular basis for the ECG features of the LQT1 form of the longQT syndrome: effects of betaadrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes[J]. Circulation,1998,98:2314-2322.

[9] Roden DM, Balser JR. A plethora of mechanisms in the HERGrelated long QT syndrome. Genetics meets electrophysiology[J]. Cardiovasc Res,1999 44:242-246.

[10]李翠兰,胡大一. 长QT综合征的最新研究进展[J].心脏杂志, 2004, 16(1):76-79.

备注/Memo

备注/Memo:
收稿日期:2004-06-14.
更新日期/Last Update: 2010-01-05