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|本期目录/Table of Contents|

QTVI结合小剂量多巴酚丁胺负荷试验检测存活心肌的评估(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第6期
页码:
555-558
栏目:
临床研究
出版日期:
2005-12-05

文章信息/Info

Title:
Assessing myocardial viability of acute myocardial infarction with quantitative tissue velocity imaging and low dose dobutamine stress echocardiography
作者:
李红玲; 周晓东; 张海滨; 张 军; 李 军; 朱 霆; 贺建国
第四军医大学西京医院超声科,陕西 西安710032
Author(s):
LI Hongling; ZHOU Xiaodong; ZHANG Haibin; ZHANG Jun; LI Jun; ZHU Ting; HE Jianguo
Department of Ultrasound, Xijing Hospital,Fourth Military Medical University,Xi'an,Shaanxi 710032,China
关键词:
组织速度成像; 组织追踪法; 心肌梗塞; 急性;  多巴酚丁胺
Keywords:
tissue velocity imaging;  tissue tracking;  myocardial infarction; acute;  dobutamine
分类号:
R542.2
DOI:
-
文献标识码:
A
摘要:
目的 应用定量组织多普勒速度成像（QTVI）结合小剂量多巴酚丁胺负荷试验(LDDS)评价存活心肌。方法 结扎犬LCX建立急性心肌梗死模型,分别于LDDS前、后记录心尖3个切面组织多普勒图像，根据QTVI在负荷前后变化特征确定存活心肌,并与三苯四氮唑溶液（TTC）染色及心肌声学造影对照。结果 LDDS前,存活心肌与非存活心肌节段间收缩期峰值速度（Vs）和收缩期最大位移（Ds）比较无显著性差异（P>0.05）， LDDS后与LDDS前相比，存活心肌节段的室壁Vs及Ds显著升高 （P<0.01）， 无存活心肌室壁Vs及Ds变化无统计学意义（P>0.05），LDDS中以负荷前后收缩期速度变化差值(△Vs)>0.66 cm/s作为截断值判断存活心肌的敏感性83％，特异性87％，以负荷前后收缩期位移变化差值(△Ds)>0.61 mm作为截断值判断存活心肌的敏感性为80％，特异性为89％。结论 应用QTVI与LDDS结合，可以检测梗死区的存活心肌。
Abstract:
AIM To explore the value of combining quantitative tissue velocity imaging (QTVI) with low-dose dobutamine stress (LDDS) in evaluating myocardial viability. METHODS The acute myocardial infarction (AMI) models were set up by ligating the LCX of dogs. After collecting the imaging information from the apical four chamber, long axis and two chamber views by using QTVI, the systolic velocity(Vs) of left ventricular(LV) wall was analyzed by tissue velocity and the systolic displacement(Ds) of LV wall was analyzed by tissue tracking（TT）. The position and the range of the myocardial infarction areas were determined with TTC staining and myocardial contrast echocardiography. The surviving myocardium was determined by the change of QTVI which reflects the myocardial contractility reserve, and compared with TTC staining and myocardial contrast echocardiography. RESULTS Before LDDS there was no significant difference of Vs and Ds between viable and unviable myocardium .The changes of Vs and Ds in the surviving myocardium segments were significant (P<0.01), while no change was found in Vs and Ds in the segments of myocardium infarction(P>0.05) after LDDS. When △Vs>0.66 mm/s was used as a threshold to determine whether the myocardium survived or not, the sensitivity was 83% and the specificity was 87%. When △Ds>0.61 mm was used as the standard, the sensitivity was 80% and specificity was 89%. CONCLUSION Combined with the LDDS, QTVI can forecast the surviving possibility of myocardia.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2004-10-19.作者简介：李红玲，主治医师，硕士生Tel:(029)83373194 Email:llixin@fmmu.edu.cn
更新日期/Last Update: 2010-01-06