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Title:: Effect of dobutamine stress test on Pwave dispersion in elderly patients with angina pectoris

作者:: 盖曙明¹; 李锡光¹; 黎明²; 1.佛山市顺德区勒流医院内科;2.佛山市顺德区人民医院检验科, 广东佛山 528322

Author(s):: GAI Shu-ming; LI　Xi-guang; LI Ming; Department of Cardiology，Lelu Hospital，Fosan，Guangdong 528322，China

关键词:: 心绞痛; 多巴酚丁胺; P波离散度; 老年

Keywords:: angina pectoris; dobutamine; Pwave dispersion; elderly

分类号:: R541.4

DOI:: -

文献标识码:: A

摘要:: 目的探讨多巴酚丁胺（Dob）负荷对老年劳累性心绞痛P波离散度（Pd）、最大P波（ Pmax）的影响。方法老年劳累性心绞痛组29例（心绞痛组）和非冠心病组10例用心电图对照静息与Dob负荷作用达“终止指标”时Pd、Pmax、最小P波（Pmin）、校正P波离散度（Pdc）及Macruz 值的变化。结果两组间静息时Pd、Pmax、Pdc、Macruz值比较无统计学差异，但Pmin比较有统计学差异；达“终止指标”时心绞痛组Pd、Pmax、Pdc及Macruz值均明显延长，Pmin缩短，组内及组间比较均有统计学差异。两组用药前后Pd＞40 ms及Pmax＞120 ms分布比较心绞痛组分别由3 例(10%)和9例(31%)增至18例(62%)和14例(48%)，Pd增加例数较非冠心病组增多（P<0.05）。结论老年劳累性心绞痛Dob负荷作用下，心房肌细胞除极的非均质性电活动变化更加明显。

Abstract:: AIM To assess the changes of Pwave dispersion （Pd）and Pwave maximum （Pmax）in the elderly patients with angina pectoris under grade dobutamine stress test. METHODS the Pd,Pmax,Pwave minimum（P min）, correct Pwave dispersion（Pdc ）, Pd/PR were observed and compared during rest and grade dobutamine stress test in 29 cases of effort angina pectoris and 10 normal controls. RESULTS The values of Pd, Pmax, Pdc and Pd/PR under rest showed no significant differences between two groups except for Pmin. Under grade dobutamine stress test when reaching “end targets”, Pd, Pmax, Pdc and Pd/PR of angina pectoris group were longer, while Pmin was shorter than those in the normal controls（P<0.05）. When the angina pectoris in the elderly group reached “end targets”, Pd＞40 ms in 18 cases (62 %) and Pmax＞120 ms in 14 cases (48 %). Compared with normal group, the number of Pd cases increased significantly（P<0.05）. CONCLUSION Under dobutamine stress elderly patients with angina pectoris, dispersion of atrial myocardial cell depolarization increases.

参考文献/References

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［3］ Dilaveris PE, Andrikopoulos GK, Metaxas G, et al. Effect of ischemia on P wave dispersion and P wave duration during spontaneous anginal episodes［J］. PACE, 1999,22(11): 1640-1647.

［4］徐方芳，王朝俭. 平板运动试验发生心绞痛患者P波离散度的变化分析［J］. 宁夏医学杂志，2002，24（10）：606-608.

［5］李锡光, 黎明, 盖曙明，等. 多巴酚丁胺负荷对劳累性心绞痛P波离散度的影响［J］. 临床心血管杂志，2003，19(12增)：44-47.

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多巴酚丁胺负荷对老年劳累性心绞痛P波离散度的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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