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双心室起搏治疗慢性心力衰竭伴心室内传导阻滞患者的近期疗效(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第2期
页码:
214-215
栏目:
临床研究
出版日期:
2006-03-01

文章信息/Info

Title:
Clinical observation of biventricular pacing in treating chronic heart failure and intraventricular conduction delay
作者:
张清; 王海昌; 刘兵; 李伟杰; 程何祥; 李成祥; 李媛; 王小燕
第四军医大学西京医院心内科,陕西 西安 710032
Author(s):
ZHANG Qing;  WANG Hai-chang;  LIU Bing;  LI Wei-jie;  CHEN He-xiang;  LI Chen-xiang;  LI Yuan;  WANG Xiao-yan
Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi′an,Shaanxi 710032, China
关键词:
双心室起搏; 心力衰竭; 心室内传导阻滞
Keywords:
biventricular pacing; heart failure; intraventricular conduction delay
分类号:
R318.11;R541.61
DOI:
-
文献标识码:
A
摘要:
目的 观察双心室起搏治疗慢性心力衰竭（心衰）的临床效果。方法 慢性心衰患者13例均伴心室内传导阻滞，体表心电图QRS波时限为146±9 ms，心功能(NYHA)Ⅲ~Ⅳ级，超声心动图显示左心室射血分数（LVEF）为0.28±0.06, 左心室舒张末径(LVEDD)为68±5 mm。患者植入三腔起搏器行心房感知，双心室起搏。结果 术后体表心电图QRS波时限缩短至122±7 ms（P<0.01）, 心功能平均提高1级。术后1月超声心动图显示LVEF增至0.36±0.06 (P<0.05), 舒张期充盈改善，二尖瓣返流减少。结论 双心室起搏可有效改善慢性心衰伴心室内传导阻滞患者近期的心功能。
Abstract:
AIM To observe the clinical effect of biventricular pacing in the treatment of chronic heart failure and intraventricular conduction delay. METHODS Thirteen patients with chronic heart failure and intraventricular conduction delay were enrolled in the study. The mean QRS width was 146±9 ms, heart function (NYHA) was class Ⅱ-Ⅲ LVEF was 0.28±0.06, and LVEDD was 68±45 mm. All of the patients received biventricular synchronous pacing. RESULTS After biventricular synchronous pacing, the mean QRS width was 122±7 ms（P<0.01, vs pretreatment）, the NYHA class of the patients was improved from class Ⅱ-Ⅲ to class Ⅱ-Ⅲ, the LVEF increased to 0.36±0.06 (P<0.05, vs pretreatment), the left ventricular filling time was increased and mitral regurgitation was reduced. CONCLUSION The biventricular synchronous pacing improves the hemodynamic effect in patients with chronic heart failure and intraventricular conduction delay.

参考文献/References

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［5］Porciani MC, Puglisi A, Colella A, et al. Echocardiographic evaluation of the effect of bivenyricular pacing: the Insync Italain Registry：The insync italian registry ［J］. Eur Heart J, 2000,2(Suppl J): J23-J30.

［6］Gras D, Mabo P, Yang T. Multisite pacing as a supplemental treatment of chronic heartfailure: preliminary results of the Medtronic InSync Study ［J］. PACE, 1998,21(10):2249-2255.

［7］Cazeau S, Leclercq C, Lavergne T, et al. Effects of multisite biventriclar pacing in patients with heart failure and intraventricular condution delay ［J］. N Engl J Med, 2001,344(5):873-880.

备注/Memo

备注/Memo:
收稿日期：2005-01-20.作者简介：张清，副教授，硕士 Tel：（029）84775183 Email：qzh60624@126.com
更新日期/Last Update: