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干细胞移植治疗冠心病的应用进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第1期
页码:
91-95
栏目:
综述
出版日期:
2007-01-01

文章信息/Info

Title:
-
作者:
王月刚 综述 吴平生 审校
南方医科大学南方医院心内科, 广东 广州 510515
Author(s):
-
关键词:
干细胞冠状动脉疾病移植
Keywords:
-
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
干细胞移植治疗急性心肌梗死在基础和临床研究中均倍受争议。目前从骨髓干细胞移植后临床试验的尸检报告已经确定干细胞可以分化成心肌细胞。目前用于移植的干细胞主要分为胚胎干细胞和成体干细胞,胚胎干细胞增殖活跃且具有全能性,但由于其安全性而很难进入临床。成体干细胞主要包括骨骼肌干细胞、骨髓干细胞以及心脏干细胞等,成体干细胞由于没有移植排斥及明显的副作用已经进入临床,其中应用较广的是骨髓干细胞,但对其有效性也充满了争议。移植的时机和方式也是目前人们关注的热点,尚没有统一的认识。干细胞移植后所引起的心肌梗死、心律失常等副作用已经引起了人们的关注。
Abstract:
-

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备注/Memo

备注/Memo:
收稿日期:2005-10-17.基金项目:国家自然科学基金项目资助(No. 30370587)作者简介:王月刚,讲师,博士生Email:wyz@fimmu.com
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