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|本期目录/Table of Contents|

无创平板运动试验评分与冠状动脉造影预后指标的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第1期
页码:
60
栏目:
临床研究
出版日期:
2009-02-28

文章信息/Info

Title:
Correlation between non-invasive Duke treadmill score and prognostic marker of coronary angiography
作者:
贾媛; 郭丹杰; 刘健; 李琪; 王伟民
北京大学人民医院心脏中心，北京100044
Author(s):
JIA Yuan;  GUO Dan-jie;  LIU Jian;  LI Qi;  WANG Wei-min
Department of Heart Center, Peking University People’s Hospital, Beijing 100044, China
关键词:
无创; 平板运动试验Duke评分; 校正的TIMI帧数; 冠状动脉疾病
Keywords:
non-invasive;  Duke treadmill score;  corrected thrombolysis in myocardial infarction frame count;  coronary disease
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨冠心病患者无创平板运动试验Duke评分（DTS）与冠状动脉造影评价预后的指标校正的TIMI帧数（CTFC）之间的相关性，为利用无创的平板运动试验评价冠心病患者的预后提供依据。 方法 对冠状动脉造影确诊为冠心病，并在造影前2周内完成平板运动试验的患者61例进行回顾性分析。根据DTS进行分组(≥5分为低危组、<5分为中高危组)，分析DTS与CTFC的相关性，比较不同危险组间CTFC的差异。结果 DTS与冠心病患者冠状动脉前降支（LAD）、回旋支（LCX）、右冠状动脉（RCA）的CTFC均呈负相关（r=-0.834、-0.769、-0.698，均P<0.01)。DTS低危组3支冠状动脉的CTFC值明显小于中高危组，组间CTFC值有明显差异\[LAD：(21.3±1.7)帧 vs (24.1±2.2)帧；LCX：(26.9±2.6)帧 vs (30.6±3.4)帧；RCA：(21.1±4.0)帧 vs (25.1±4.3)帧，均P<0.01\]。结论 冠心病患者平板运动试验Duke评分与LAD、LCX、RCA的CTFC值呈负相关。根据DTS得出的危险分层与CTFC有良好的相关性。
Abstract:
AIM To investigate the correlation between the non-invasive Duke treadmill score (DTS) and the corrected thrombolysis in myocardial infarction frame count (CTFC) in patients with coronary atherosclerotic heart disease. METHODS A total of 61 patients with coronary atherosclerotic heart disease, who underwent treadmill exercise tests at least 2 weeks before coronary angiography, were enrolled in our study. According to the value of DTS, we divided patients into 2 groups: low-risk group (DTS≥5) and moderate-high-risk group (DTS<5), and the correlation between DTS and CTFC was evaluated. RESULTSDTS correlated negatively with CTFC of left anterior descending (LAD), left circumflex artery (LCX) and right coronary artery (RCA) (r=-0.834,-0.769,-0.698,P<0.01). CTFC in the low-risk group was much lower than that in the moderate-high-risk group \[LAD: (21.3±1.7) vs (24.1±2.2), LCX: (26.9±2.6) vs (30.6±3.4), RCA:(21.1±4.0) vs (25.1±4.3), P<0.01\]. CONCLUSION There is a negative correlation between DTS and CTFC of LAD, LCX and RCA in patients with CAD. The risk stratification on the basis of DTS is notably associated with CTFC.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2007-8-31.基金项目：北京大学人民医院研究与发展基金（RDC2007-07） 通讯作者：郭丹杰，教授，主要从事与冠心病、高血压、高脂血症的相关研究Email:danjieheart@sohu.com 作者简介：贾媛，硕士生Email:jiayuan0507@sohu.com
更新日期/Last Update: 2009-04-02