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|本期目录/Table of Contents|

VEGF对冠心病血管新生的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第3期
页码:
410-413
栏目:
综述
出版日期:
2009-05-15

文章信息/Info

Title:
-
作者:
王冰12李晶华1综述王宗仁1审校
1.第四军医大学西京医院中医科,陕西 西安 710032;2.解放军538医院,陕西 汉中 723000
Author(s):
-
关键词:
血管内皮细胞生长因子血管新生动脉粥样硬化
Keywords:
-
分类号:
R543
DOI:
-
文献标识码:
A
摘要:
本文以血管内皮细胞生长因子(VEGF)及其受体在血管新生中的生物学效应为基础,围绕着血管新生在缺血性心脏病中的作用,讨论了VEGF对动脉粥样硬化血管新生的影响,分析了VEGF生物作用多样性可能与浓度相关性调整有关。
Abstract:
-

参考文献/References

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[3] Khurana R, Simons M, Martin JF, et al. Role of angiogenesis in cardiovascular disease: a critical appraisal[J]. Circulation, 2005, 112(12):1813-1824.

[4] Hervé MA, Meduri G, Petit FG, et al. Regulation of the vascular endothelial growth factor (VEGF) receptor Flk-1/KDR by estradiol through VEGF in uterus[J]. J Endocrinol, 2006, 188(1):91-99.

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[6] 张彩萍,肖传实. 内皮祖细胞在成体新血管生成中的作用[J]. 心血管病学进展, 2007, 28(1):85-88.

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[8] Simons M. Angiogenesis: where do we stand now? [J]. Circulation, 2005, 111(12):1556-1566.

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[10]Leppnen P, Koota S, Kholov I, et al. Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/apolipoprotein B48-deficient mice[J]. Circulation, 2005, 112(9):1347-1352.

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[12]Futami R, Miyashita M, Nomura T, et al. Increased serum vascular endothelial growth factor following major surgical injury[J]. J Nippon Med Sch, 2007, 74(3):223-229.

[13]Pufe T, Lemke A, Kurz B, et al. Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor[J]. Am J Pathol, 2004, 164 (1):185-92.

[14]Doege K, Heine S, Jensen I, et al. Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxiaúinducible factor (HIF) intact[J]. Blood, 2005, 106(7):2311-2317.

[15]Epstein SE, Stabile E, Kinnaird T, et al. Janus phenomenon: the interrelated tradeoffs inherent in therapies designed to enhance collateral formation and those designed to inhibit atherogenesis[J]. Circulation, 2004, 109(23):2826-2831.

[16]汪俊元,王安才. 他汀类药物对血管重构的干预机制[J]. 心脏杂志,2006, 18(3):356-358.

[17]Shiojima I, Walsh K. The role of vascular endothelial growth factor in restenosis: the controversy continues[J]. Circulation, 2004, 110(16):2283-2286.

备注/Memo

备注/Memo:
收稿日期:2007-8-31.通讯作者:王宗仁,教授,主任医师,主要从事中药防治心脑血管病的研究Email:zongren@fmmu.edu.cn 作者简介:王冰,住院医师,硕士生Email:tuhai77@sohu.com
更新日期/Last Update: 2009-05-18