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|本期目录/Table of Contents|

TLR4信号通路与动脉粥样硬化的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第4期
页码:
572-574
栏目:
综述
出版日期:
2009-06-25

文章信息/Info

Title:
-
作者:
盛富强1综述; 程龙献2审校
1.郧阳医学院附属太和医院心内科，湖北 十堰 442000； 2.华中科技大学同济医学院附属协和医院心内科，湖北 武汉 430022
Author(s):
-
关键词:
TLR4; 动脉粥样硬化; 信号通路
Keywords:
-
分类号:
R543.5
DOI:
-
文献标识码:
A
摘要:
近年来，研究TLR4信号通路在动脉粥样硬化（AS）中的作用成为心血管领域中的一个热点。本文就TLR4的结构、功能、信号转导机制及其与AS之间关系的体内、体外试验依据和基因学依据作一综述。
Abstract:
-

参考文献/References

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［11］Ameziane N, Beillat T, Verpillat P, et al. Association of the toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events［J］. Arterioscler Thromb Vasc Biol， 2003， 23(12):e61-e64.

［12］Boekholdt SM, Agema WR, Peters RJ, et al. Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events［J］. Circulation, 2003, 107(19):2416-2421.

［13］Edfeldt K, Bennet AM, Eriksson P,et al. Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction［J］. Eur Heart J, 2004, 25(16):1447-1453.

［14］Netea MG, Hijmans A, van Wissen S, et al. Toll-like receptor-4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia［J］. Eur J Clin Invest, 2004, 34(2):94-99.

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备注/Memo

备注/Memo:
收稿日期：2007-3-16.作者简介：盛富强，主治医师，博士生Email:shengfuqiang@yahoo.com.cn
更新日期/Last Update: 2009-06-15