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|本期目录/Table of Contents|

高血压病患者胰岛素抵抗与动脉弹性指数的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第5期
页码:
686-688
栏目:
临床研究
出版日期:
2009-07-14

文章信息/Info

Title:
Correlating factors of insulin resistance in essential hypertension and its relation to arterial elasticity
作者:
田红燕; 马爱群; 韩克; 刘亚; 胡志; 王廷忠; 耿涛
西安交通大学医学院第一附属医院心内科，陕西 西安710061
Author(s):
TIAN Hong-yan;  MA Ai-qun;  HAN Ke;  LIU Ya;  HU Zhi;  WANG Ting-zhong;  GENG Tao
Department of Cardiology, First Affiliated Hospital, Medical College of Xian Jiaotong University, Xian 710061, Shaanxi, China
关键词:
高血压; 原发性; 胰岛素抵抗; 动脉弹性
Keywords:
hypertension;  primary;  insulin resistance;  arterial elasticity
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的: 分析动脉弹性指数与高血压病患者胰岛素抵抗相关因素之间的相关性。方法: 测定112例高血压病患者动脉弹性指数与血压、糖脂代谢及红细胞内Mg2+，Ca2+离子等指标，并对各项指标进行相关及回归分析。结果: 高血压病患者大动脉弹性指数（C1）和小动脉弹性指数（C2）与胰岛素敏感指数（ISI）呈正相关，它们均与收缩压、舒张压及平均动脉压、体质量指数、血清三酰甘油和红细胞内Mg2+呈负相关。结论: 高血压病患者胰岛素抵抗相关因素与动脉弹性指数之间有相关性。
Abstract:
AIM: To explore the relation between arterial elasticity and the correlate factors of insulin resistance in essential hypertension. METHODS: Five indices, namely, arterial elasticity, blood pressure, glucose and lipid metabolism, erythrocyte intracellular magnesium level and erythrocytes were analyzed in 112 patients with essential hypertension. RESULTS: A positive correlation was observed between insulin sensitivity and large artery elasticity indices (C1) as well as small artery elasticity indices (C2), whereas insulin sensitivity and arterial elasticity indices exhibited a negative correlation with blood pressure, body mass index, serum levels of triglyceride and erythrocyte intracellular magnesium level. CONCLUSION: Arterial elasticity in essential hypertension is correlated with insulin resistance.

参考文献/References

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［3］ Milyagina IV, Milyagin VA, Pozdnyakov YM, et al. Age dynamics of blood pressure in various vascular basins among healthy people and patients with arterial hypertension［J］. Cardiovasc Therapy Prev, 2008, 7(2):44-50.

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［6］ Tian H, Ma A, Li C, et al. Correlative factors of insulin resistance in essential hypertension［J］. Hypertens Res, 2000, 23(3):265-270.

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［8］ Terai M, Ohishi M, Ito N, et al. Comparison of arterial functional evaluations as a predictor of cardiovascular events in hypertensive patients: The non-invasive atherosclerotic evaluation in hypertension (NOAH) study［J］. Hypertens Res, 2008, 31(6):1135-1145.

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备注/Memo

备注/Memo:
收稿日期：2008-10-22.基金项目：西安交通大学21世纪振兴教育行动计划资助（TZ044） 作者简介：田红燕，副教授Email:tianhhyy@mail.xjtu.edu.cn
更新日期/Last Update: 2009-07-22