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|本期目录/Table of Contents|

老年原发性高血压患者晨峰现象与左心室肥厚

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第2期
页码:
225-227
栏目:
临床研究
出版日期:
2010-03-04

文章信息/Info

Title:
Association between morning blood pressure surge and left ventricular hypertrophy in elderly patients with essential hypertension
作者:
马丽娜1; 冯明1; 马佳2
首都医科大学宣武医院:1.综合科，2.超声诊断科，北京 100053
Author(s):
MA Li-na1;  FENG Ming1;  MA Jia2
1.Department of Integrated Medicine, 2.Department of Ultrasound Diagnosis, Xuanwu Hospital, Capital University of Medical Science, Beijing 100053, China
关键词:
高血压; 原发性; 晨峰现象; 左心室肥厚; 老年人
Keywords:
hypertension;  morning blood pressure surge;  left ventricular hypertrophy;  elderly
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的: 探讨老年原发性高血压晨峰现象与左心室肥厚的关系。方法: 老年原发性高血压患者107例根据24 h动态血压监测分为有晨峰现象（MBPS）组（40例）和无晨峰现象（NMBPS）组（67例），检查空腹血脂、血糖和肌酐，并计算体质量指数（BMI）和左室质量指数（LVMI）。结果: MBPS组的24 h动态血压监测收缩压高于NMBPS组（P<0.05）。MBPS组的LVMI显著高于NMBPS组［（132±28）g/m2 vs.(113±28)g/m2，P<0.01］。结论: 老年原发性高血压有晨峰现象者更易发生左心室肥厚。
Abstract:
AIM: To explore the association between morning blood pressure surge (MBPS) and left ventricular hypertrophy in elderly patients with essential hypertension. METHODS: One hundred and seven patients under 24 h ambulatory blood pressure monitoring were categorized as with MBPS (n=40) and no MBPS (NMBPS) (n=67) and their total cholesterol, body mass index (BMI) and left ventricular mass index (LVMI) were determined. RESULTS: Systolic blood pressure in MBPS was higher than in NMBPS (P<0.05). LVMI in MBPS was higher than in NMBPS ［(132± 28) g/m2 vs.(113±28) g/m2, P<0.01］. CONCLUSION: Morning blood pressure surge is closely related with the development of left ventricular hypertrophy in elderly patients with essential hypertension.

参考文献/References

［1］ White WB. Cardiovascular risk and therapeutic intervention for the early morning surge in blood pressure and heart rate［J］. Blood Press Monit, 2001, 6（2）：63-72.

［2］ 郭艺芳，胡大一. 血压的晨峰现象及其临床意义［J］. 中华全科医师杂志， 2007， 6(9)：521-523.

［3］ Kario K, Picketing TG, Hoshide S, et al. Morning blood pressure surge and hypertensive cerebrovascular disease. Role of the alpha adrenergic sympathetic nervous system［J］. Am J Hypertens, 2004, 17（8）：668-675.

［4］ Paolo V, Giancarlo C, Antonio C, et al. Left ventricular mass and cardiovascular morbidity in essential hypertension: The MAVI Study［J］. J Am Coll Cardiol, 2001, 38（7）：1829-1835.

［5］ 黄绮芳，李燕，王继光. 血压晨峰［J］. 中华心血管病杂志， 2008， 36(1)：91-93.

［6］ Kario K. Morning surge and variability in blood pressure：a new therapeutic target?［J］. Hypertens, 2005, 45（4）：485-486．

［7］ Gosse P, Lasserre R, Minifie C, et al. Blood pressure surge on rising［J］. J Hypertens, 2004, 22（6）：1113-1118.

［8］ 骆丽菊. 老年高血压患者血压晨峰与心脏重构的关系探讨［J］. 心脑血管病防治， 2007， 7（4）：255-256.

［9］ 孙宁玲，喜杨，荆珊，等. 原发性高血压患者凌晨血压增高与年龄、性别的相关性研究［J］. 中国循环杂志， 2006， 21(2)：103-105.

备注/Memo

备注/Memo:
收稿日期：2008-10-28.作者简介：马丽娜，主治医师，硕士Email:malina0883@yahoo.com.cn
更新日期/Last Update: 2010-03-05