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|本期目录/Table of Contents|

冠心病并发焦虑症的临床治疗分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第5期
页码:
744-746
栏目:
临床研究
出版日期:
2010-06-22

文章信息/Info

Title:
Analysis of clinical treatment of coronary heart disease and anxiety disorders
作者:
张勇进; 刘芙蓉; 但蓓蓓
神农架第一人民医院心内科，湖北 神农架442400
Author(s):
ZHANG Yong-jin;  LIU Fu-rong;  DAN Bei-bei
Department of Cardiovasology, Shengnongjia First Renmin Hospital, Shengnongjia 442400, Hubei, China
关键词:
冠状动脉疾病; 焦虑症; 治疗; 抗焦虑药物
Keywords:
coronary disease;  anxiety disorder;  therapy;  anti-anxiety medication
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 研究冠心病并发焦虑症患者同时接受小剂量抗焦虑药物治疗对冠心病治疗的影响。方法: 40例冠心病并发焦虑症患者随机分成试药组和常规组，试药组在常规组基础上加用小剂量抗焦虑药物治疗，用药4周后分别比较临床心绞痛发作次数，心电图改善程度，以及焦虑症状评定。结果: 两组患者同等劳动程度心绞痛发作次数均明显减少，试药组总有效率为96%，常规组总有效率为79%，差异有显著性（P<0.05）。两组心电图总有效率（试药组84%，常规组85%）比较差异无统计学意义，两组治疗后SAS分数均有下降，但常规组差异无统计学意义，试药组SAS分数显著下降（P<0.05），差异有统计学意义，评分亦明显低于常规组(P<0.05)，提示试药组的焦虑症状较常规组明显改善。结论: 加用小剂量抗焦虑药物，在同等劳动程度下心绞痛发作次数明显减少，患者的焦虑症状也得到有效改善。
Abstract:
AIM: To explore the effect of low-dose anti-anxiety medication in the treatment of coronary heart disease (CHD) in patients with both CHD and anxiety disorders. METHODS: Forty cases of CHD and anxiety disorder were randomly divided into treatment group and conventional group. In addition to the conventional treatment, patients in the treatment group were given low-dose anti-anxiety medication. Four weeks after treatment, the occurrence of angina pectoris, ECG improvement and anxiety symptom assessment were compared between groups. RESULTS: Under the same workload, the occurrence of angina pectoris was significantly reduced in both groups and the total effective rate in the treatment group was 96%, whereas that in the conventional group was 79%, with significant difference between groups (P<0.05). No significant difference was observed in the effective rate of ECG between groups (treatment group 84% vs. conventional group 85%). After treatment, SAS scores in both groups declined, but significant differences were only found in the treatment group (P<0.05). The SAS scores in the treatment group were significantly lower than in the conventional group (P<0.05), demonstrating that anxiety symptoms in the treatment group were significantly more improved in the treatment group. CONCLUSION: Low-dose anti-anxiety drugs significantly reduce the occurrence of angina pectoris, effectively alleviate anxiety symptoms and improve the quality of life in patients with both CHD and anxiety disorders.

参考文献/References

［1］代华磊,杨蓓,李建美,等. 冠心病与焦虑症［J］. 心血管病学进展, 2008, 29(1):71-73.

［2］杨菊贤,蔡文玮. 心血管疾病患者中抑郁和焦虑障碍的躯体症状［J］. 上海预防医学杂志, 2002, 14(1):46-47.

［3］ 井海云. 急性心肌梗死患者抗焦虑抑郁治疗的临床观察［J］. 心脏杂志, 2007, 19(5):546.

［4］Barger SD, Sydeman SJ. Does generalized anxiety disorder predict coronary heart disease risk factors independently of major depressive disorder?［J］. J Affect Disord, 2005, 88(1):87-91.

备注/Memo

备注/Memo:
收稿日期：2009-06-23.作者简介：张勇进,主治医师Email：snjzhyj@qq.com
更新日期/Last Update: 2010-06-22